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Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion

Publication ,  Journal Article
Mitchell, TG; Turner, SR
Published in: Medical Mycology
January 1, 1984

A potent chemotactic activity for neutrophils is detectable in liquid culture filtrates of Blastomyces dermatitidis. The production of this activity is medium-dependent and culture age-dependent. The highest levels of cytotaxin were produced in filtrates of B. dermatitidis grown in tissue culture medium 199 for three or more weeks. This factor(s) stimulates directed as well as random migration. It functions directly and independently of serum. It is stable at -20°C and 56°C, and has a molecular weight greater than 10 000 daltons. These properties define a new microbial chemotactic factor. © 1984 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Duke Scholars

Published In

Medical Mycology

DOI

ISSN

1369-3786

Publication Date

January 1, 1984

Volume

22

Issue

2

Start / End Page

145 / 153

Related Subject Headings

  • Microbiology
  • 1108 Medical Microbiology
 

Citation

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MLA
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Mitchell, T. G., & Turner, S. R. (1984). Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion. Medical Mycology, 22(2), 145–153. https://doi.org/10.1080/00362178485380221
Mitchell, T. G., and S. R. Turner. “Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion.” Medical Mycology 22, no. 2 (January 1, 1984): 145–53. https://doi.org/10.1080/00362178485380221.
Mitchell TG, Turner SR. Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion. Medical Mycology. 1984 Jan 1;22(2):145–53.
Mitchell, T. G., and S. R. Turner. “Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion.” Medical Mycology, vol. 22, no. 2, Jan. 1984, pp. 145–53. Scopus, doi:10.1080/00362178485380221.
Mitchell TG, Turner SR. Effects of culture filtrates of blastomyces dermatitidis on neutrophil locomotion. Medical Mycology. 1984 Jan 1;22(2):145–153.
Journal cover image

Published In

Medical Mycology

DOI

ISSN

1369-3786

Publication Date

January 1, 1984

Volume

22

Issue

2

Start / End Page

145 / 153

Related Subject Headings

  • Microbiology
  • 1108 Medical Microbiology