Single- and multiple-track-location shear wave and acoustic radiation force impulse imaging: matched comparison of contrast, contrast-to-noise ratio and resolution.

Journal Article (Journal Article)

Acoustic radiation force impulse imaging and shear wave elasticity imaging (SWEI) use the dynamic response of tissue to impulsive mechanical stimulus to characterize local elasticity. A variant of conventional, multiple-track-location SWEI, denoted single-track-location SWEI, offers the promise of creating speckle-free shear wave images. This work compares the three imaging modalities using a high push and track beam density combined acquisition sequence to image inclusions of different sizes and contrasts. Single-track-location SWEI is found to have a significantly higher contrast-to-noise ratio than multiple-track-location SWEI, allowing for operation at higher resolution. Acoustic radiation force impulse imaging and single-track-location SWEI perform similarly in the larger inclusions, with single-track-location SWEI providing better visualization of small targets ≤ 2.5 mm in diameter. The processing of each modality introduces different trade-offs between smoothness and resolution of edges and structures; these are discussed in detail.

Full Text

Duke Authors

Cited Authors

  • Hollender, PJ; Rosenzweig, SJ; Nightingale, KR; Trahey, GE

Published Date

  • April 2015

Published In

Volume / Issue

  • 41 / 4

Start / End Page

  • 1043 - 1057

PubMed ID

  • 25701531

Pubmed Central ID

  • PMC4346467

Electronic International Standard Serial Number (EISSN)

  • 1879-291X

International Standard Serial Number (ISSN)

  • 0301-5629

Digital Object Identifier (DOI)

  • 10.1016/j.ultrasmedbio.2014.11.006


  • eng