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Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction.

Publication ,  Journal Article
Hai, OY; Mentz, RJ; Zannad, F; Gasparini, M; De Ferrari, GM; Daubert, J-C; Holzmeister, J; Lam, CSP; Pochet, T; Vincent, A; Linde, C
Published in: Eur J Heart Fail
February 2015

Cardiac resynchronization therapy is beneficial in heart failure patients with LVEF ≤35% and electrical dyssynchrony. However, its effects among patients with less severe LV dysfunction have not been established. Recent post-hoc analyses of landmark CRT trials suggest that CRT benefit may be present in patients with LVEF >35% and is associated with improvement in cardiac reverse remodelling, all-cause mortality, and need for heart failure hospitalizations. This review summarizes the currently available literature regarding the potential impact of CRT in patients with more modest reductions in LVEF.

Duke Scholars

Published In

Eur J Heart Fail

DOI

EISSN

1879-0844

Publication Date

February 2015

Volume

17

Issue

2

Start / End Page

135 / 143

Location

England

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Stroke Volume
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Cardiac Resynchronization Therapy
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Hai, O. Y., Mentz, R. J., Zannad, F., Gasparini, M., De Ferrari, G. M., Daubert, J.-C., … Linde, C. (2015). Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction. Eur J Heart Fail, 17(2), 135–143. https://doi.org/10.1002/ejhf.208
Hai, Ofek Y., Robert J. Mentz, Faiez Zannad, Maurizio Gasparini, Gaetano M. De Ferrari, Jean-Claude Daubert, Johannes Holzmeister, et al. “Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction.Eur J Heart Fail 17, no. 2 (February 2015): 135–43. https://doi.org/10.1002/ejhf.208.
Hai OY, Mentz RJ, Zannad F, Gasparini M, De Ferrari GM, Daubert J-C, et al. Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction. Eur J Heart Fail. 2015 Feb;17(2):135–43.
Hai, Ofek Y., et al. “Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction.Eur J Heart Fail, vol. 17, no. 2, Feb. 2015, pp. 135–43. Pubmed, doi:10.1002/ejhf.208.
Hai OY, Mentz RJ, Zannad F, Gasparini M, De Ferrari GM, Daubert J-C, Holzmeister J, Lam CSP, Pochet T, Vincent A, Linde C. Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction. Eur J Heart Fail. 2015 Feb;17(2):135–143.
Journal cover image

Published In

Eur J Heart Fail

DOI

EISSN

1879-0844

Publication Date

February 2015

Volume

17

Issue

2

Start / End Page

135 / 143

Location

England

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Stroke Volume
  • Humans
  • Heart Failure
  • Cardiovascular System & Hematology
  • Cardiac Resynchronization Therapy
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology