Wellens syndrome: a life-saving diagnosis.


Journal Article

The diagnosis of acute coronary syndrome relies on clinical history, electrocardiographic (ECG) changes, and cardiac biomarkers; but within the spectrum of acute coronary syndrome, there exist subtle presentations that cannot afford to be overlooked. Wellens syndrome is one such example, in which a patient can present with both ECG changes that are not classic for myocardial ischemia and negative cardiac biomarkers. The characteristic ECG findings associated with Wellens syndrome consist of deep, symmetric T-wave inversions in the anterior precordial leads. However, Wellens syndrome can also present as biphasic T-wave inversions in those same ECG leads. The associated critical stenosis of the proximal left anterior descending artery carries an immediately life-threatening prognosis if not recognized promptly (Am Heart J. 1982;103[4 Pt 2]:730-736). We describe a case of a less common manifestation of Wellens syndrome (type 1) followed by a discussion of its implications and management.

Full Text

Duke Authors

Cited Authors

  • Parikh, KS; Agarwal, R; Mehrotra, AK; Swamy, RS

Published Date

  • January 2012

Published In

Volume / Issue

  • 30 / 1

Start / End Page

  • 255.e3 - 255.e5

PubMed ID

  • 21106319

Pubmed Central ID

  • 21106319

Electronic International Standard Serial Number (EISSN)

  • 1532-8171

Digital Object Identifier (DOI)

  • 10.1016/j.ajem.2010.10.014


  • eng

Conference Location

  • United States