New Developments in Insomnia Medications of Relevance to Mental Health Disorders.

Journal Article (Journal Article;Review)

Many insomnia medications with high specificity have become available recently. They provide a window into the clinical effects of modulating specific brain systems and establish a new guiding principal for conceptualizing insomnia medications: "mechanism matters." A new paradigm for insomnia therapy in which specific drugs are selected to target the specific type of sleep difficulty for each patient includes administering specific treatments for patients with insomnia comorbid with particular psychiatric disorders. This article reviews insomnia medications and discusses the implications for optimizing the treatment of insomnia occurring comorbid with psychiatric conditions.

Full Text

Duke Authors

Cited Authors

  • Krystal, AD

Published Date

  • December 2015

Published In

Volume / Issue

  • 38 / 4

Start / End Page

  • 843 - 860

PubMed ID

  • 26600112

Pubmed Central ID

  • PMC5972036

Electronic International Standard Serial Number (EISSN)

  • 1558-3147

Digital Object Identifier (DOI)

  • 10.1016/j.psc.2015.08.001


  • eng

Conference Location

  • United States