Maternal Effects of Respiratory Syncytial Virus Infection during Pregnancy.

Journal Article (Journal Article)

Given the illness and deaths caused by respiratory syncytial virus (RSV) infection during the first year of life, preventing infant RSV infections through maternal vaccination is intriguing. However, little is known about the extent and maternal effects of RSV infection during pregnancy. We describe 3 cases of maternal RSV infection diagnosed at a US center during winter 2014. Case-patient 1 (26 years old, week 33 of gestation) received a diagnosis of RSV infection and required mechanical ventilation. Case-patient 2 (27 years old, week 34 of gestation) received a diagnosis of infection with influenza A(H1N1) virus and RSV and required mechanical ventilation. Case-patient 3 (21 years old, week 32 of gestation) received a diagnosis of group A streptococcus pharyngitis and RSV infection and was monitored as an outpatient. Clarifying the effects of maternal RSV infection could yield valuable insights into potential maternal and fetal benefits of an effective RSV vaccination program.

Full Text

Duke Authors

Cited Authors

  • Wheeler, SM; Dotters-Katz, S; Heine, RP; Grotegut, CA; Swamy, GK

Published Date

  • November 2015

Published In

Volume / Issue

  • 21 / 11

Start / End Page

  • 1951 - 1955

PubMed ID

  • 26485575

Pubmed Central ID

  • PMC4622246

Electronic International Standard Serial Number (EISSN)

  • 1080-6059

Digital Object Identifier (DOI)

  • 10.3201/eid2111.150497


  • eng

Conference Location

  • United States