Mouse models of metastatic pancreatic adenocarcinoma.

Journal Article (Review)

Pancreatic adenocarcinoma is a deadly disease. Its etiology is unknown, and metastatic disease kills the majority of patients who have it. Effective prevention is clearly the ultimate goal for eradicating this disease provided that the effects of environmental and genetic elements on pancreatic cancer development are fully understood. Currently, it appears that the control of pancreatic cancer metastasis is of immediate urgency. Fulfillment of this difficult task relies on knowledge of the cellular and molecular biology of metastasis. The use of relevant animal models will help define each aspect of this complicated process.

Full Text

Duke Authors

Cited Authors

  • Xie, K; Wang, B; Shi, Q; Abbruzzese, JL; Xiong, Q; Le, X

Published Date

  • January 2001

Published In

Volume / Issue

  • 29 / 1

Start / End Page

  • 25 - 35

PubMed ID

  • 11558630

International Standard Serial Number (ISSN)

  • 0169-4197

Digital Object Identifier (DOI)

  • 10.1385/ijgc:29:1:25

Language

  • eng