Overview
My research interests include the clinical study and treatment of pancreatic cancer.
Current Appointments & Affiliations
D.C.I. Distinguished Professor Emeritus of Medical Oncology
·
2024 - Present
Medicine, Medical Oncology,
Medicine
Professor Emeritus of Medicine
·
2024 - Present
Medicine, Medical Oncology,
Medicine
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Perioperative and Oncologic Outcomes of Hepatic Arterial Infusion (HAI) Pump Chemotherapy for Patients with Unresectable Colorectal Liver Metastases at an Expanding HAI Program.
Conference Ann Surg Oncol · February 2025 BACKGROUND: Hepatic arterial infusion (HAI) is an established treatment for patients with unresectable colorectal liver metastases (uCRLM). Until recently, HAI was only performed at a limited number of centers. We previously reported early outcomes suggest ... Full text Link to item CiteCharacterization of the Biological Variability of the Angiome Biomarkers over Time in Healthy Participants.
Journal Article Cancer Epidemiol Biomarkers Prev · January 9, 2025 BACKGROUND: Biomarker analyses are an integral part of cancer research. Despite the intense efforts to identify and characterize biomarkers in patients with cancer, little is known regarding the natural variation of biomarkers in healthy populations. Here ... Full text Link to item CiteEditor's Note: Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells.
Journal Article Clin Cancer Res · December 2, 2024 Full text Link to item CiteRecent Grants
A phase 1/1b/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of AMG 193 alone and in combination with docetaxel in subjects with advanced MTAP-null solid tumors
Clinical TrialPrincipal Investigator · Awarded by Amgen, Inc. · 2024 - 2027A PHASE 1 DOSE ESCALATION AND EXPANSION STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTITUMOR ACTIVITY OF PF-07257876 IN PATIENTS WITH ADVANCED OR METASTATIC TUMORS
Clinical TrialPrincipal Investigator · Awarded by Pfizer, Inc. · 2021 - 2026A Window-of-Opportunity Trial Using Neoadjuvant Hepatic Artery Chemotherapy for Patients With Localized Pancreas Cancer
ResearchCollaborator · Awarded by Marc Lustgarten Pancreatic Cancer Foundation · 2023 - 2026View All Grants
Education, Training & Certifications
The University of Chicago ·
1978
M.D.