Molecular and genetic approaches for the analysis of C. elegans neuronal development.
Journal Article (Journal Article)
The complete known anatomical connections of C. elegans nervous system have provided researchers ample opportunities to discover fundamental principles underlying neuronal development. Transgenic labeling with fluorescent proteins in neuronal cells has had an unparalleled impact on our ability to visualize cellular architecture and dynamics. In this chapter, we summarize the common methods and guidelines for dissecting the molecular and cellular mechanisms controlling nervous system formation. We end with a brief description of several applications that illustrate the use of these methods.
Full Text
Duke Authors
Cited Authors
- Yan, D; Jin, Y
Published Date
- 2011
Published In
Volume / Issue
- 106 /
Start / End Page
- 413 - 443
PubMed ID
- 22118286
International Standard Serial Number (ISSN)
- 0091-679X
Digital Object Identifier (DOI)
- 10.1016/B978-0-12-544172-8.00015-3
Language
- eng
Conference Location
- United States