Molecular and genetic approaches for the analysis of C. elegans neuronal development.

Journal Article

The complete known anatomical connections of C. elegans nervous system have provided researchers ample opportunities to discover fundamental principles underlying neuronal development. Transgenic labeling with fluorescent proteins in neuronal cells has had an unparalleled impact on our ability to visualize cellular architecture and dynamics. In this chapter, we summarize the common methods and guidelines for dissecting the molecular and cellular mechanisms controlling nervous system formation. We end with a brief description of several applications that illustrate the use of these methods.

Full Text

Duke Authors

Cited Authors

  • Yan, D; Jin, Y

Published Date

  • January 2011

Published In

Volume / Issue

  • 106 /

Start / End Page

  • 413 - 443

PubMed ID

  • 22118286

International Standard Serial Number (ISSN)

  • 0091-679X

Digital Object Identifier (DOI)

  • 10.1016/b978-0-12-544172-8.00015-3

Language

  • eng