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Dong Yan

Associate Professor of Molecular Genetics and Microbiology
Molecular Genetics and Microbiology


we are interested in understanding the molecular mechanisms underlying neural circuit formation during development and degeneration in aging. In my lab, We use a free-living tiny roundworm, called Caenorhabditis elegans, as a model. The defined cell lineage, completely mapped connectome and rapid life cycle of this organism greatly facilitate investigating nervous system at the subcellular resolution. Combining classic genetic analysis with in vivo live imaging technique and molecular and cellular manipulations, we are discovering conserved mechanisms playing key roles in neural circuit formation, gap junction dynamics and neurodegeneration

Current Appointments & Affiliations

Associate Professor of Molecular Genetics and Microbiology · 2022 - Present Molecular Genetics and Microbiology, Basic Science Departments
Associate Professor in Neurobiology · 2022 - Present Neurobiology, Basic Science Departments
Associate Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Faculty Network Member of the Duke Institute for Brain Sciences · 2013 - Present Duke Institute for Brain Sciences, University Institutes and Centers
Affiliate of the Duke Regeneration Center · 2021 - Present Regeneration Next Initiative, Basic Science Departments

Education, Training & Certifications

Chinese Academy of Sciences, Shanghai Institute for Biological Sciences (China) · 2006 Ph.D.