A model of muscle atrophy using cast immobilization in mice.
Publication
, Journal Article
Frimel, TN; Kapadia, F; Gaidosh, GS; Li, Y; Walter, GA; Vandenborne, K
Published in: Muscle Nerve
November 2005
We describe a new cast-immobilization protocol to induce muscle atrophy in the lower hindlimb muscles of mice. Bilateral cast immobilization for 2 weeks in a shortened position resulted in a significant loss of muscle size and strength in the soleus and extensor digitorum longus. The availability of a model of cast immobilization in mice may benefit future studies targeting genetic or cell therapy interventions of muscle atrophy in transgenic and mutant mice strains.
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Published In
Muscle Nerve
DOI
ISSN
0148-639X
Publication Date
November 2005
Volume
32
Issue
5
Start / End Page
672 / 674
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Muscular Atrophy
- Models, Animal
- Mice, Inbred C57BL
- Mice
- Hindlimb Suspension
- Female
- Animals
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Frimel, T. N., Kapadia, F., Gaidosh, G. S., Li, Y., Walter, G. A., & Vandenborne, K. (2005). A model of muscle atrophy using cast immobilization in mice. Muscle Nerve, 32(5), 672–674. https://doi.org/10.1002/mus.20399
Frimel, Tiffany N., Fatema Kapadia, Gabriel S. Gaidosh, Ye Li, Glenn A. Walter, and Krista Vandenborne. “A model of muscle atrophy using cast immobilization in mice.” Muscle Nerve 32, no. 5 (November 2005): 672–74. https://doi.org/10.1002/mus.20399.
Frimel TN, Kapadia F, Gaidosh GS, Li Y, Walter GA, Vandenborne K. A model of muscle atrophy using cast immobilization in mice. Muscle Nerve. 2005 Nov;32(5):672–4.
Frimel, Tiffany N., et al. “A model of muscle atrophy using cast immobilization in mice.” Muscle Nerve, vol. 32, no. 5, Nov. 2005, pp. 672–74. Pubmed, doi:10.1002/mus.20399.
Frimel TN, Kapadia F, Gaidosh GS, Li Y, Walter GA, Vandenborne K. A model of muscle atrophy using cast immobilization in mice. Muscle Nerve. 2005 Nov;32(5):672–674.
Published In
Muscle Nerve
DOI
ISSN
0148-639X
Publication Date
November 2005
Volume
32
Issue
5
Start / End Page
672 / 674
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Muscular Atrophy
- Models, Animal
- Mice, Inbred C57BL
- Mice
- Hindlimb Suspension
- Female
- Animals
- 32 Biomedical and clinical sciences
- 31 Biological sciences