Type I interferon pathway in adult and juvenile dermatomyositis.
Journal Article (Journal Article;Review)
Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.
Full Text
Duke Authors
Cited Authors
- Baechler, EC; Bilgic, H; Reed, AM
Published Date
- 2011
Published In
Volume / Issue
- 13 / 6
Start / End Page
- 249 -
PubMed ID
- 22192711
Pubmed Central ID
- PMC3334651
Electronic International Standard Serial Number (EISSN)
- 1478-6362
Digital Object Identifier (DOI)
- 10.1186/ar3531
Language
- eng
Conference Location
- England