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Type I interferon pathway in adult and juvenile dermatomyositis.

Publication ,  Journal Article
Baechler, EC; Bilgic, H; Reed, AM
Published in: Arthritis Res Ther
2011

Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.

Duke Scholars

Published In

Arthritis Res Ther

DOI

EISSN

1478-6362

Publication Date

2011

Volume

13

Issue

6

Start / End Page

249

Location

England

Related Subject Headings

  • Up-Regulation
  • Signal Transduction
  • Interferon-beta
  • Interferon-alpha
  • Interferon Type I
  • Humans
  • Gene Expression Profiling
  • Dermatomyositis
  • Child
  • Arthritis & Rheumatology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Baechler, E. C., Bilgic, H., & Reed, A. M. (2011). Type I interferon pathway in adult and juvenile dermatomyositis. Arthritis Res Ther, 13(6), 249. https://doi.org/10.1186/ar3531
Baechler, Emily C., Hatice Bilgic, and Ann M. Reed. “Type I interferon pathway in adult and juvenile dermatomyositis.Arthritis Res Ther 13, no. 6 (2011): 249. https://doi.org/10.1186/ar3531.
Baechler EC, Bilgic H, Reed AM. Type I interferon pathway in adult and juvenile dermatomyositis. Arthritis Res Ther. 2011;13(6):249.
Baechler, Emily C., et al. “Type I interferon pathway in adult and juvenile dermatomyositis.Arthritis Res Ther, vol. 13, no. 6, 2011, p. 249. Pubmed, doi:10.1186/ar3531.
Baechler EC, Bilgic H, Reed AM. Type I interferon pathway in adult and juvenile dermatomyositis. Arthritis Res Ther. 2011;13(6):249.

Published In

Arthritis Res Ther

DOI

EISSN

1478-6362

Publication Date

2011

Volume

13

Issue

6

Start / End Page

249

Location

England

Related Subject Headings

  • Up-Regulation
  • Signal Transduction
  • Interferon-beta
  • Interferon-alpha
  • Interferon Type I
  • Humans
  • Gene Expression Profiling
  • Dermatomyositis
  • Child
  • Arthritis & Rheumatology