Type I interferon pathway in adult and juvenile dermatomyositis.

Journal Article (Journal Article;Review)

Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.

Full Text

Duke Authors

Cited Authors

  • Baechler, EC; Bilgic, H; Reed, AM

Published Date

  • 2011

Published In

Volume / Issue

  • 13 / 6

Start / End Page

  • 249 -

PubMed ID

  • 22192711

Pubmed Central ID

  • PMC3334651

Electronic International Standard Serial Number (EISSN)

  • 1478-6362

Digital Object Identifier (DOI)

  • 10.1186/ar3531

Language

  • eng

Conference Location

  • England