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Ann Marie Reed

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics
2301 Erwin Road, Box 3352, Durham, NC 27710
Not Shown, Not Shown, NC 27710

Overview


I have spent my career caring for children with autoimmune disorders and immune dysfunction.  I have focused my work caring for children with juvenile dermatomyositis and auto inflammatory disorders.  I have overseen a research program for 24 years studying the  genetics and cause of human autoimmune disease, focused on dermatomyositis in children and adults. The long-term goal of my research team is to develop new biomarkers of diseases to identify those predisposed to develop disease, as well as monitor disease activity and response to treatment. My team makes extensive use of genomics, gene expression, protein expression and immunohistochemical techniques to study the inflammatory and non-inflammatory aspects of dermatomyositis diseases. Other autoimmune disease processes, including systemic lupus and vasculitis, have been focused on as well.

Current Appointments & Affiliations


Samuel L. Katz Distinguished Professor of Pediatrics · 2018 - Present Pediatrics, Clinical Science Departments
Professor of Pediatrics · 2014 - Present Pediatrics, Clinical Science Departments

In the News


Published May 1, 2015
Duke Announces 2015 Distinguished Professors

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Recent Publications


Juvenile idiopathic inflammatory myopathies assessment by magnetic resonance imaging: a scoping review of protocols, scoring systems, and applications.

Journal Article Adv Rheumatol · November 21, 2025 BACKGROUND:: Our review assessed whole body (WB) and dedicated body-part magnetic resonance imaging (DedMRI) techniques, protocols, and inflammatory scoring systems, focusing on their clinimetric properties (reliability, validity, responsiveness) in clinic ... Full text Link to item Cite

HLA loci heterozygosity modulates genetic risk in idiopathic inflammatory myopathies.

Journal Article Ann Rheum Dis · October 2025 OBJECTIVES: Idiopathic inflammatory myopathies (IIMs) are rare autoimmune disorders. Genetic association studies have highlighted the role of human leukocyte antigen (HLA) polymorphisms in IIM. We aimed to characterise the nonadditive effects (dominance an ... Full text Link to item Cite

Shared genetic susceptibility between idiopathic inflammatory myopathies and common B cell lymphoma subtypes found primarily in the human leucocyte antigen region.

Journal Article RMD Open · August 25, 2025 OBJECTIVES: To estimate shared genetic susceptibility between major subtypes of idiopathic inflammatory myopathies (IIM) and B cell lymphomas. METHODS: We paired summary statistics from genome-wide association studies (GWASs) of diffuse large B cell lympho ... Full text Link to item Cite
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Recent Grants


Using Bioengineered Human Muscle to Develop Treatments for Juvenile Dermatomyositis

ResearchCollaborator · Awarded by Hartwell Foundation · 2025 - 2028

An Invitation to Support the Division of Pediatric Gastroenterology, Hepatology & Nutrition

ResearchInvestigator · Awarded by Mario Family Foundation · 2022 - 2026

Using bioengineered human muscle to understand mechanisms of juvenile dermatomyositis

ResearchAdvisor · Awarded by Childhood Arthritis & Rheumatology Research Alliance, Inc. · 2025 - 2026

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Education, Training & Certifications


Medical College of Ohio · 1984 M.D.