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Ann Marie Reed

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics
2301 Erwin Road, Box 3352, Durham, NC 27710
Not Shown, Not Shown, NC 27710

Overview


I have spent my career caring for children with autoimmune disorders and immune dysfunction.  I have focused my work caring for children with juvenile dermatomyositis and auto inflammatory disorders.  I have overseen a research program for 24 years studying the  genetics and cause of human autoimmune disease, focused on dermatomyositis in children and adults. The long-term goal of my research team is to develop new biomarkers of diseases to identify those predisposed to develop disease, as well as monitor disease activity and response to treatment. My team makes extensive use of genomics, gene expression, protein expression and immunohistochemical techniques to study the inflammatory and non-inflammatory aspects of dermatomyositis diseases. Other autoimmune disease processes, including systemic lupus and vasculitis, have been focused on as well.

Current Appointments & Affiliations


Samuel L. Katz Distinguished Professor of Pediatrics · 2018 - Present Pediatrics, Clinical Science Departments
Professor of Pediatrics · 2014 - Present Pediatrics, Clinical Science Departments
Chair, Department of Pediatrics · 2014 - Present Pediatrics, Clinical Science Departments
Core Faculty in Innovation & Entrepreneurship · 2021 - Present Duke Innovation & Entrepreneurship, University Initiatives & Academic Support Units

In the News


Published May 1, 2015
Duke Announces 2015 Distinguished Professors

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Recent Publications


Genetic Architecture of Idiopathic Inflammatory Myopathies From Meta-Analyses.

Journal Article Arthritis Rheumatol · December 16, 2024 OBJECTIVE: Idiopathic inflammatory myopathies (IIMs, myositis) are rare systemic autoimmune disorders that lead to muscle inflammation, weakness, and extramuscular manifestations, with a strong genetic component influencing disease development and progress ... Full text Link to item Cite

A protocol for scoping reviews on the role of whole-body and dedicated body-part magnetic resonance imaging for assessment of adult and juvenile idiopathic inflammatory myopathies.

Journal Article Rheumatol Int · November 2024 Currently, standardized magnetic resonance imaging (MRI) scoring systems and protocols for assessment of idiopathic inflammatory myopathies (IIMs) in children and adults are lacking. Therefore, we will perform a scoping review of the literature to collate ... Full text Link to item Cite

Atherosclerosis Progression in the APPLE Trial Can Be Predicted in Young People With Juvenile-Onset Systemic Lupus Erythematosus Using a Novel Lipid Metabolomic Signature.

Journal Article Arthritis Rheumatol · March 2024 OBJECTIVE: Patients with juvenile-onset systemic lupus erythematosus (JSLE) have increased atherosclerosis risk. This study investigated novel atherosclerosis progression biomarkers in the Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) ... Full text Link to item Cite
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Recent Grants


Using Bioengineered Human Muscle to Develop Treatments for Juvenile Dermatomyositis

ResearchCollaborator · Awarded by Hartwell Foundation · 2025 - 2028

An Invitation to Support the Division of Pediatric Gastroenterology, Hepatology & Nutrition

ResearchInvestigator · Awarded by Mario Family Foundation · 2022 - 2026

Duke Center for Advancement of Child Health (CAtCH).

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2021 - 2026

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Education, Training & Certifications


Medical College of Ohio · 1984 M.D.