Compromised atrial coronary anatomy is associated with atrial arrhythmias and atrioventricular block complicating acute myocardial infarction.
Journal Article
BACKGROUND: The relevance of the atrial coronary anatomy in the pathogenesis of atrial arrhythmias and atrioventricular (AV) block complicating acute myocardial infarction (AMI) remains unclear. OBJECTIVES: We evaluated the location of the infarct-related coronary lesion relative to the principal atrial branches (ie, sinoatrial nodal, AV nodal, left atrial circumflex) in 454 patients with ST-elevation AMI in the CAPTORS II trial. METHODS: Patients underwent systematic 60-minute postfibrinolytic angiograms, and coronary anatomy was correlated with evidence of atrial arrhythmias and AV block on sequential electrocardiograms. RESULTS: Patients with either sinoatrial nodal or left atrial circumflex compromise (n = 34) had a higher incidence of "early" (ie, up to 90 minutes postfibrinolysis) atrial arrhythmias vs those without (23.5% vs 7.1%; P = .004). Patients with AV nodal compromise (n = 207) had a higher incidence of "early" AV block vs those without (12.1% vs 3.6%; P = .001). CONCLUSION: These findings support the etiological role of acute atrial ischemia in the development of early atrial arrhythmias and AV block complicating AMI.
Full Text
Duke Authors
Cited Authors
- Tjandrawidjaja, MC; Fu, Y; Kim, DH; Burton, JR; Lindholm, L; Armstrong, PW; CAPTORS II Investigators,
Published Date
- July 2005
Published In
Volume / Issue
- 38 / 3
Start / End Page
- 271 - 278
PubMed ID
- 16003715
Electronic International Standard Serial Number (EISSN)
- 1532-8430
International Standard Serial Number (ISSN)
- 0022-0736
Digital Object Identifier (DOI)
- 10.1016/j.jelectrocard.2005.01.013
Language
- eng