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Paul Wayne Armstrong

Adjunct Professor in the Department of Medicine
Medicine, Cardiology

Current Appointments & Affiliations


Adjunct Professor in the Department of Medicine · 2015 - Present Medicine, Cardiology, Medicine

Recent Publications


Pharmaco-invasive strategy and dosing of tenecteplase in STEMI patients 60 to <75 years: An inter-trial comparison of the STREAM-1 and STREAM-2 trials.

Journal Article Am Heart J · June 2025 BACKGROUND: Previous studies indicate a safety risk with full-dose TNK in elderly patients. In a study of patients ≥60 years STREAM-2 (STrategic Reperfusion Early After Myocardial infarction-2), a pharmaco-invasive (PI) strategy with half-dose TNK was simi ... Full text Link to item Cite

Projecting the benefit of vericiguat in PARADIGM-HF and DAPA-HF populations: Insights from the VICTORIA trial.

Journal Article ESC Heart Fail · April 2025 AIMS: The VICTORIA trial demonstrated a significant reduction in the primary composite outcome of heart failure (HF) hospitalization or cardiovascular death with vericiguat relative to placebo in high-risk HF. This study aimed to contextualize treatment ef ... Full text Link to item Cite

Comparing Analytical Methods for Composite End Points in Clinical Trials: Insights from the Vericiguat Global Study in Subjects with Heart Failure With Reduced Ejection Fraction Trial.

Journal Article J Card Fail · March 2025 BACKGROUND: In VICTORIA (Vericiguat Global Study in Subjects with Heart Failure with Reduced Ejection Fraction), participants with heart failure (HF) and reduced ejection fraction, vericiguat decreased the primary composite outcome (time to first HF hospit ... Full text Link to item Cite
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Education, Training & Certifications


Queens University · 1966 M.D.