Challenges and opportunities in implementing pharmacogenomics testing in the clinics.

Journal Article (Journal Article)

The field of pharmacogenomics aims to incorporate individual patient genomic information into treatment selection. This is a rapidly evolving field with significant clinical promise. Implementation into clinical practice has several challenges that must be overcome. Genomics-based information encompasses large databases and requires expert knowledge for interpretation. Existing research suggests there are already several areas where pharmacogenomics-based decision-making is ripe for adoption into clinical practice. Impediments exist that must be overcome prior to large-scale implementation of existing pharmacogenomics-based therapies. There are several institutions and corporations at the forefront of implementation that are leading the development; however, larger systems-based approaches will be necessary. This article will discuss some of the present successes and future challenges that are necessary to overcome in order to implement a more patient-centered healthcare system.

Full Text

Duke Authors

Cited Authors

  • Wisler, JR; Wisler, JW; Bansal, S; Marsh, CB

Published Date

  • August 2012

Published In

Volume / Issue

  • 9 / 6

Start / End Page

  • 609 - 619

PubMed ID

  • 29768798

Electronic International Standard Serial Number (EISSN)

  • 1744-828X

Digital Object Identifier (DOI)

  • 10.2217/pme.12.64


  • eng

Conference Location

  • England