Optical-resolution photoacoustic endomicroscopy in vivo.
Journal Article (Journal Article)
Optical-resolution photoacoustic microscopy (OR-PAM) has become a major experimental tool of photoacoustic tomography, with unique imaging capabilities for various biological applications. However, conventional imaging systems are all table-top embodiments, which preclude their use in internal organs. In this study, by applying the OR-PAM concept to our recently developed endoscopic technique, called photoacoustic endoscopy (PAE), we created an optical-resolution photoacoustic endomicroscopy (OR-PAEM) system, which enables internal organ imaging with a much finer resolution than conventional acoustic-resolution PAE systems. OR-PAEM has potential preclinical and clinical applications using either endogenous or exogenous contrast agents.
Full Text
Duke Authors
Cited Authors
- Yang, J-M; Li, C; Chen, R; Rao, B; Yao, J; Yeh, C-H; Danielli, A; Maslov, K; Zhou, Q; Shung, KK; Wang, LV
Published Date
- March 2015
Published In
Volume / Issue
- 6 / 3
Start / End Page
- 918 - 932
PubMed ID
- 25798315
Pubmed Central ID
- PMC4361445
Electronic International Standard Serial Number (EISSN)
- 2156-7085
International Standard Serial Number (ISSN)
- 2156-7085
Digital Object Identifier (DOI)
- 10.1364/boe.6.000918
Language
- eng