© 2016 by the American Anthropological Association. All rights reserved. This essay critiques mismatch theory in science education, a theory supported by opponents of affirmative action who strive to derail efforts to diversify institutions of higher education. Can high-achieving students survive and thrive in an academic environment dominated by their super high-achieving peers? Our research suggests that while there are a variety of nuanced factors that impact an undergraduate's success in certain majors, students of all backgrounds can excel at highly selective universities, given the proper resources and support.