Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.

Journal Article

Herein we report the synthesis and investigation of the properties of two tris-cyclometalated luminescent iridium complexes. These complexes are the simple derivatives of fac-[Ir(ppy)3] bearing amino alkyl groups on one of the phenylpyridine rings. The complexes are highly emissive and exhibit structured emission peaks in aqueous solution while having only broad unstructured emission in organic solvents. The complexes have been shown to be taken up by NIH-3T3 and PC3 cells, where they localize in the lysosomes and remain emissive with lifetimes in the microsecond domain.

Full Text

Duke Authors

Cited Authors

  • Sansee, A; Meksawangwong, S; Chainok, K; Franz, KJ; Gál, M; Pålsson, L-O; Puniyan, W; Traiphol, R; Pal, R; Kielar, F

Published Date

  • November 2016

Published In

Volume / Issue

  • 45 / 43

Start / End Page

  • 17420 - 17430

PubMed ID

  • 27734036

Electronic International Standard Serial Number (EISSN)

  • 1477-9234

International Standard Serial Number (ISSN)

  • 1477-9226

Digital Object Identifier (DOI)

  • 10.1039/c6dt02776h

Language

  • eng