Systemic associations of dynamic retinal vessel analysis: a review of current literature.
Published
Journal Article (Review)
Endothelial dysfunction is a key pathogenic mechanism of CVD. The retinal microvascular network offers a unique, non-invasive window to study endothelial function. Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in CVD. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race/ethnicity. These data suggest that flicker light-induced retinal vasodilation may be a unique and non-invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light-induced retinal vasodilation, and discusses the potential for future research in this area.
Full Text
Duke Authors
Cited Authors
- Lim, M; Sasongko, MB; Ikram, MK; Lamoureux, E; Wang, JJ; Wong, TY; Cheung, CY
Published Date
- April 2013
Published In
Volume / Issue
- 20 / 3
Start / End Page
- 257 - 268
PubMed ID
- 23151190
Pubmed Central ID
- 23151190
Electronic International Standard Serial Number (EISSN)
- 1549-8719
Digital Object Identifier (DOI)
- 10.1111/micc.12026
Language
- eng
Conference Location
- United States