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Systemic associations of dynamic retinal vessel analysis: a review of current literature.

Publication ,  Journal Article
Lim, M; Sasongko, MB; Ikram, MK; Lamoureux, E; Wang, JJ; Wong, TY; Cheung, CY
Published in: Microcirculation
April 2013

Endothelial dysfunction is a key pathogenic mechanism of CVD. The retinal microvascular network offers a unique, non-invasive window to study endothelial function. Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in CVD. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race/ethnicity. These data suggest that flicker light-induced retinal vasodilation may be a unique and non-invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light-induced retinal vasodilation, and discusses the potential for future research in this area.

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Published In

Microcirculation

DOI

EISSN

1549-8719

Publication Date

April 2013

Volume

20

Issue

3

Start / End Page

257 / 268

Location

United States

Related Subject Headings

  • Vasodilation
  • Retinal Vessels
  • Retina
  • Metabolic Diseases
  • Light
  • Hypertension
  • Humans
  • Endothelium, Vascular
  • Cardiovascular System & Hematology
  • Animals
 

Citation

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Lim, M., Sasongko, M. B., Ikram, M. K., Lamoureux, E., Wang, J. J., Wong, T. Y., & Cheung, C. Y. (2013). Systemic associations of dynamic retinal vessel analysis: a review of current literature. Microcirculation, 20(3), 257–268. https://doi.org/10.1111/micc.12026
Lim, Michelle, Muhammad B. Sasongko, Mohammad K. Ikram, Ecosse Lamoureux, Jie Jin Wang, Tien Yin Wong, and Carol Y. Cheung. “Systemic associations of dynamic retinal vessel analysis: a review of current literature.Microcirculation 20, no. 3 (April 2013): 257–68. https://doi.org/10.1111/micc.12026.
Lim M, Sasongko MB, Ikram MK, Lamoureux E, Wang JJ, Wong TY, et al. Systemic associations of dynamic retinal vessel analysis: a review of current literature. Microcirculation. 2013 Apr;20(3):257–68.
Lim, Michelle, et al. “Systemic associations of dynamic retinal vessel analysis: a review of current literature.Microcirculation, vol. 20, no. 3, Apr. 2013, pp. 257–68. Pubmed, doi:10.1111/micc.12026.
Lim M, Sasongko MB, Ikram MK, Lamoureux E, Wang JJ, Wong TY, Cheung CY. Systemic associations of dynamic retinal vessel analysis: a review of current literature. Microcirculation. 2013 Apr;20(3):257–268.
Journal cover image

Published In

Microcirculation

DOI

EISSN

1549-8719

Publication Date

April 2013

Volume

20

Issue

3

Start / End Page

257 / 268

Location

United States

Related Subject Headings

  • Vasodilation
  • Retinal Vessels
  • Retina
  • Metabolic Diseases
  • Light
  • Hypertension
  • Humans
  • Endothelium, Vascular
  • Cardiovascular System & Hematology
  • Animals