Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART
Publication
, Journal Article
Evans, WJ; Kotler, DP; Staszewski, S; Griffin, GE; Isgaard, J; Gertner, JM; O'Brien, F; Svanberg, E
Published in: AIDS Reader
January 1, 2005
Over 700 patients with HIV-associated wasting while receiving HAART were randomly assigned to double-blind treatment for 12 weeks with recombinant human growth hormone (rhGH) daily or on alternate days, or to placebo. Maximum exercise intensity increased by a median of 2.35 kJ in the alternate-days group and 2.60 kJ in the daily group but decreased by 0.25 kJ in the placebo group. The median difference between the daily and placebo groups was 2.85 kJ (P < .0001). These improvements suggest that rhGH treatment may enable patients with wasting to perform activities of daily living that would be exhausting without rhGH treatment.
Duke Scholars
Published In
AIDS Reader
ISSN
1053-0894
Publication Date
January 1, 2005
Volume
15
Issue
6
Related Subject Headings
- Virology
Citation
APA
Chicago
ICMJE
MLA
NLM
Evans, W. J., Kotler, D. P., Staszewski, S., Griffin, G. E., Isgaard, J., Gertner, J. M., … Svanberg, E. (2005). Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Reader, 15(6).
Evans, W. J., D. P. Kotler, S. Staszewski, G. E. Griffin, J. Isgaard, J. M. Gertner, F. O’Brien, and E. Svanberg. “Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.” AIDS Reader 15, no. 6 (January 1, 2005).
Evans WJ, Kotler DP, Staszewski S, Griffin GE, Isgaard J, Gertner JM, et al. Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Reader. 2005 Jan 1;15(6).
Evans, W. J., et al. “Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.” AIDS Reader, vol. 15, no. 6, Jan. 2005.
Evans WJ, Kotler DP, Staszewski S, Griffin GE, Isgaard J, Gertner JM, O’Brien F, Svanberg E. Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Reader. 2005 Jan 1;15(6).
Published In
AIDS Reader
ISSN
1053-0894
Publication Date
January 1, 2005
Volume
15
Issue
6
Related Subject Headings
- Virology