Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase.
Journal Article (Journal Article)
Adenine phosphoribosyltransferase from the protozoan parasite Leishmania donovani has been crystallized in the presence of the substrate Mg(2+)-alpha-D-5-phosphoribosyl-1-pyrophosphate (PRPP) or the product adenosine-5-monophosphate, as well as in the absence of ligand. These crystals belong to the space group P6(1)22 or its enantiomorph P6(5)22, with unit cell dimensions of a = b = 64.0 A, c = 240.5 A, alpha = beta = 90 degrees, and gamma = 120 degrees. The crystals diffract to 1.9 A.
Full Text
Duke Authors
Cited Authors
- Phillíps, CL; Ullman, B; Brennan, RG
Published Date
- August 1996
Published In
Volume / Issue
- 25 / 4
Start / End Page
- 510 - 513
PubMed ID
- 8865346
International Standard Serial Number (ISSN)
- 0887-3585
Digital Object Identifier (DOI)
- 10.1002/prot.11
Language
- eng
Conference Location
- United States