Reduction in pulmonary and hepatic respiratory cytochrome contents by fly ash inhalation in rats.
Exposure of rats to fly ash for 15 days, 6 hours daily, inhibited pulmonary and hepatic NADH-oxidase activity. The content of cytochrome b and cytochromes a + a3 was significantly lower in the lungs of the fly-ash-exposed group. However, in liver, fly ash exposure reduced the cytochrome a + a3 level without affecting the cytochrome b content, indicating a tissue-specific effect. Mitochondrial protein content in both organs was the same in both groups.
Chauhan, SS; Tyagi, SR; Kapoor, RK; Misra, UK
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