Developmental pattern of DNA and proteins in brain, liver, lung and heart of rats given excess vitamin A postnatally.

Journal Article (Journal Article)

The effect of an excessive dose of vitamin A (1,000 IU) to rat pups on 4, 6, 8 and 10 days of age was studied on growth and organ weights. The effects on the amounts of DNA and proteins and incorporation of 3H-thymidine into DNA and 3H-leucine into proteins of brain, liver, lung and heart was studied on 11, 17 and 23 days of age. Excess vitamin A administration affected the postnatal development of DNA and protein metabolism of these organs differently.

Full Text

Duke Authors

Cited Authors

  • Shukla, RR; Joshi, HC; Misra, UK

Published Date

  • 1983

Published In

Volume / Issue

  • 44 / 4

Start / End Page

  • 243 - 250

PubMed ID

  • 6626632

International Standard Serial Number (ISSN)

  • 0006-3126

Digital Object Identifier (DOI)

  • 10.1159/000241721


  • eng

Conference Location

  • Switzerland