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Quantitative and Qualitative Comparison of Single-Source Dual-Energy Computed Tomography and 120-kVp Computed Tomography for the Assessment of Pancreatic Ductal Adenocarcinoma.

Publication ,  Journal Article
Bhosale, P; Le, O; Balachandran, A; Fox, P; Paulson, E; Tamm, E
Published in: J Comput Assist Tomogr
2015

PURPOSE: The aim of this study was to compare contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) between pancreatic-phase dual-energy computed tomography (DECT) and 120-kVp CT for pancreatic ductal adenocarcinoma (PDA). MATERIALS AND METHODS: Seventy-eight patients underwent multiphasic pancreatic imaging protocols for PDA (40, DECT; 38, 120-kVp CT [control]). Using pancreatic phase, CNR and SNR for PDA were obtained for DECT at monochromatic energies 50 through 80 keV, iodine material density images, and 120-kVp images. Using a 5-point scale (1, excellent; 5, markedly limited), images were qualitatively assessed by 2 radiologists in consensus for PDA detection, extension, vascular involvement, and noise. Wilcoxon signed rank and 2-sample tests were used to compare the qualitative measures, CNR and SNR, for DECT and 120-kVp images. Bonferroni correction was applied. RESULTS: Iodine material density image had significantly higher CNR and SNR for PDA than any monochromatic energy images (P < 0.0001) and the 120-kVp images. Qualitatively, 70-keV images were rated highest in the categories of tumor extension and vascular invasion and were similar to 120-kVp images. CONCLUSIONS: Our results indicate that DECT improves PDA lesion conspicuity compared with routine 120-kVp CT, which may allow for better detection of PDA.

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Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2015

Volume

39

Issue

6

Start / End Page

907 / 913

Location

United States

Related Subject Headings

  • Triiodobenzoic Acids
  • Tomography, X-Ray Computed
  • Signal-To-Noise Ratio
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Pancreatic Neoplasms
  • Pancreas
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
 

Citation

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Bhosale, P., Le, O., Balachandran, A., Fox, P., Paulson, E., & Tamm, E. (2015). Quantitative and Qualitative Comparison of Single-Source Dual-Energy Computed Tomography and 120-kVp Computed Tomography for the Assessment of Pancreatic Ductal Adenocarcinoma. J Comput Assist Tomogr, 39(6), 907–913. https://doi.org/10.1097/RCT.0000000000000295
Bhosale, Priya, Ott Le, Aprana Balachandran, Patricia Fox, Eric Paulson, and Eric Tamm. “Quantitative and Qualitative Comparison of Single-Source Dual-Energy Computed Tomography and 120-kVp Computed Tomography for the Assessment of Pancreatic Ductal Adenocarcinoma.J Comput Assist Tomogr 39, no. 6 (2015): 907–13. https://doi.org/10.1097/RCT.0000000000000295.
Bhosale, Priya, et al. “Quantitative and Qualitative Comparison of Single-Source Dual-Energy Computed Tomography and 120-kVp Computed Tomography for the Assessment of Pancreatic Ductal Adenocarcinoma.J Comput Assist Tomogr, vol. 39, no. 6, 2015, pp. 907–13. Pubmed, doi:10.1097/RCT.0000000000000295.

Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2015

Volume

39

Issue

6

Start / End Page

907 / 913

Location

United States

Related Subject Headings

  • Triiodobenzoic Acids
  • Tomography, X-Ray Computed
  • Signal-To-Noise Ratio
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Pancreatic Neoplasms
  • Pancreas
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male