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Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation.

Publication ,  Journal Article
McClellan, T; Allen, BC; Kappus, M; Bhatti, L; Dafalla, RA; Snyder, LD; Bashir, MR
Published in: Curr Probl Diagn Radiol
2017

PURPOSE: To determine interreader and intrareader repeatability and correlations among measurements of computerized tomography-based anthropomorphic measurements in patients with pulmonary fibrosis undergoing lung transplantation. METHODS: This was an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study of 23 randomly selected subjects (19 male and 4 female; median age = 69 years; range: 66-77 years) with idiopathic pulmonary fibrosis undergoing pulmonary transplantation, who had also undergone preoperative thoracoabdominal computerized tomography. Five readers of varying imaging experience independently performed the following cross-sectional area measurements at the inferior endplate of the L3 vertebral body: right and left psoas muscles, right and left paraspinal muscles, total abdominal musculature, and visceral and subcutaneous fat. The following measurements were obtained at the inferior endplate of T6: right and left paraspinal muscles with and without including the trapezius muscles and subcutaneous fat. Three readers repeated all measurements to assess intrareader repeatability. RESULTS: Intrareader repeatability was nearly perfect (interclass correlation coefficients = 0.99, P < 0.001). Interreader agreement was excellent across all 5 readers (interclass correlation coefficients: 0.71-0.99, P < 0.001). Coefficients of variance between measures ranged from 3.2%-6.8% for abdominal measurements, but were higher for thoracic measurements, up to 23.9%. Correlation between total paraspinal and total psoas muscle area was strong (r2 = 0.67, P < 0.001). Thoracic and abdominal musculature had a weaker correlation (r2 = 0.35-0.38, P < 0.001). CONCLUSION: Measures of thoracic and abdominal muscle and fat area are highly repeatable in patients with pulmonary fibrosis undergoing lung transplantation. Measures of muscle area are strongly correlated among abdominal locations, but inversely correlated between abdominal and thoracic locations.

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Published In

Curr Probl Diagn Radiol

DOI

EISSN

1535-6302

Publication Date

2017

Volume

46

Issue

4

Start / End Page

300 / 304

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sarcopenia
  • Retrospective Studies
  • Reproducibility of Results
  • Pulmonary Fibrosis
  • Nuclear Medicine & Medical Imaging
  • Male
  • Lung Transplantation
  • Iopamidol
  • Humans
 

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McClellan, T., Allen, B. C., Kappus, M., Bhatti, L., Dafalla, R. A., Snyder, L. D., & Bashir, M. R. (2017). Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation. Curr Probl Diagn Radiol, 46(4), 300–304. https://doi.org/10.1067/j.cpradiol.2016.12.009
McClellan, Taylor, Brian C. Allen, Matthew Kappus, Lubna Bhatti, Randa A. Dafalla, Laurie D. Snyder, and Mustafa R. Bashir. “Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation.Curr Probl Diagn Radiol 46, no. 4 (2017): 300–304. https://doi.org/10.1067/j.cpradiol.2016.12.009.
McClellan T, Allen BC, Kappus M, Bhatti L, Dafalla RA, Snyder LD, et al. Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation. Curr Probl Diagn Radiol. 2017;46(4):300–4.
McClellan, Taylor, et al. “Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation.Curr Probl Diagn Radiol, vol. 46, no. 4, 2017, pp. 300–04. Pubmed, doi:10.1067/j.cpradiol.2016.12.009.
McClellan T, Allen BC, Kappus M, Bhatti L, Dafalla RA, Snyder LD, Bashir MR. Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation. Curr Probl Diagn Radiol. 2017;46(4):300–304.
Journal cover image

Published In

Curr Probl Diagn Radiol

DOI

EISSN

1535-6302

Publication Date

2017

Volume

46

Issue

4

Start / End Page

300 / 304

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sarcopenia
  • Retrospective Studies
  • Reproducibility of Results
  • Pulmonary Fibrosis
  • Nuclear Medicine & Medical Imaging
  • Male
  • Lung Transplantation
  • Iopamidol
  • Humans