Skip to main content
Journal cover image

Parent-delivered early intervention in infants at risk for ASD: Effects on electrophysiological and habituation measures of social attention.

Publication ,  Journal Article
Jones, EJH; Dawson, G; Kelly, J; Estes, A; Webb, SJ
Published in: Autism Res
May 2017

Prospective longitudinal studies of infants with older siblings with autism spectrum disorder (ASD) have indicated that differences in the neurocognitive systems underlying social attention may emerge prior to the child meeting ASD diagnostic criteria. Thus, targeting social attention with early intervention might have the potential to alter developmental trajectories for infants at high risk for ASD. Electrophysiological and habituation measures of social attention were collected at 6, 12, and 18 months in a group of high-risk infant siblings of children with ASD (N = 33). Between 9 and 11 months of age, infant siblings received a parent-delivered intervention, promoting first relationships (PFR), (n = 19) or on-going assessment without intervention (n = 14). PFR has been previously shown to increase parental responsivity to infant social communicative cues and infant contingent responding. Compared to infants who only received assessment and monitoring, infants who received the intervention showed improvements in neurocognitive metrics of social attention, as reflected in a greater reduction in habituation times to face versus object stimuli between 6 and 12 months, maintained at 18 months; a greater increase in frontal EEG theta power between 6 and 12 months; and a more comparable P400 response to faces and objects at 12 months. The high-risk infants who received the intervention showed a pattern of responses that appeared closer to the normative responses of two groups of age-matched low-risk control participants. Though replication is necessary, these results suggest that early parent-mediated intervention has the potential to impact the brain systems underpinning social attention in infants at familial risk for ASD. Autism Res 2017, 10: 961-972. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Autism Res

DOI

EISSN

1939-3806

Publication Date

May 2017

Volume

10

Issue

5

Start / End Page

961 / 972

Location

United States

Related Subject Headings

  • Social Behavior
  • Siblings
  • Risk Factors
  • Prospective Studies
  • Parents
  • Male
  • Infant
  • Humans
  • Habituation, Psychophysiologic
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jones, E. J. H., Dawson, G., Kelly, J., Estes, A., & Webb, S. J. (2017). Parent-delivered early intervention in infants at risk for ASD: Effects on electrophysiological and habituation measures of social attention. Autism Res, 10(5), 961–972. https://doi.org/10.1002/aur.1754
Jones, Emily J. H., Geraldine Dawson, Jean Kelly, Annette Estes, and Sara Jane Webb. “Parent-delivered early intervention in infants at risk for ASD: Effects on electrophysiological and habituation measures of social attention.Autism Res 10, no. 5 (May 2017): 961–72. https://doi.org/10.1002/aur.1754.
Jones, Emily J. H., et al. “Parent-delivered early intervention in infants at risk for ASD: Effects on electrophysiological and habituation measures of social attention.Autism Res, vol. 10, no. 5, May 2017, pp. 961–72. Pubmed, doi:10.1002/aur.1754.
Journal cover image

Published In

Autism Res

DOI

EISSN

1939-3806

Publication Date

May 2017

Volume

10

Issue

5

Start / End Page

961 / 972

Location

United States

Related Subject Headings

  • Social Behavior
  • Siblings
  • Risk Factors
  • Prospective Studies
  • Parents
  • Male
  • Infant
  • Humans
  • Habituation, Psychophysiologic
  • Female