Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.

Journal Article (Journal Article)

Current literature makes a distinction between two pathways for thyroid hormone signaling: genomic and nongenomic. However, this classification is a source of confusion. We propose a clarification in the nomenclature that may help to avoid unproductive controversies and favor progress in this field of research. Four types of thyroid hormone signaling are defined, and the experimental criteria for classification are discussed.

Full Text

Duke Authors

Cited Authors

  • Flamant, F; Cheng, S-Y; Hollenberg, AN; Moeller, LC; Samarut, J; Wondisford, FE; Yen, PM; Refetoff, S

Published Date

  • July 1, 2017

Published In

Volume / Issue

  • 158 / 7

Start / End Page

  • 2052 - 2057

PubMed ID

  • 28472304

Pubmed Central ID

  • PMC6283428

Electronic International Standard Serial Number (EISSN)

  • 1945-7170

Digital Object Identifier (DOI)

  • 10.1210/en.2017-00250


  • eng

Conference Location

  • United States