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Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.

Publication ,  Journal Article
Flamant, F; Cheng, S-Y; Hollenberg, AN; Moeller, LC; Samarut, J; Wondisford, FE; Yen, PM; Refetoff, S
Published in: Endocrinology
July 1, 2017

Current literature makes a distinction between two pathways for thyroid hormone signaling: genomic and nongenomic. However, this classification is a source of confusion. We propose a clarification in the nomenclature that may help to avoid unproductive controversies and favor progress in this field of research. Four types of thyroid hormone signaling are defined, and the experimental criteria for classification are discussed.

Duke Scholars

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Published In

Endocrinology

DOI

EISSN

1945-7170

Publication Date

July 1, 2017

Volume

158

Issue

7

Start / End Page

2052 / 2057

Location

United States

Related Subject Headings

  • Transcription Factors
  • Thyroid Hormones
  • Terminology as Topic
  • Signal Transduction
  • Receptors, Thyroid Hormone
  • Humans
  • Endocrinology & Metabolism
  • DNA
  • Animals
  • 3202 Clinical sciences
 

Citation

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Flamant, F., Cheng, S.-Y., Hollenberg, A. N., Moeller, L. C., Samarut, J., Wondisford, F. E., … Refetoff, S. (2017). Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. Endocrinology, 158(7), 2052–2057. https://doi.org/10.1210/en.2017-00250
Flamant, Frédéric, Sheue-Yann Cheng, Anthony N. Hollenberg, Lars C. Moeller, Jacques Samarut, Fredric E. Wondisford, Paul M. Yen, and Samuel Refetoff. “Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.Endocrinology 158, no. 7 (July 1, 2017): 2052–57. https://doi.org/10.1210/en.2017-00250.
Flamant F, Cheng S-Y, Hollenberg AN, Moeller LC, Samarut J, Wondisford FE, et al. Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. Endocrinology. 2017 Jul 1;158(7):2052–7.
Flamant, Frédéric, et al. “Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.Endocrinology, vol. 158, no. 7, July 2017, pp. 2052–57. Pubmed, doi:10.1210/en.2017-00250.
Flamant F, Cheng S-Y, Hollenberg AN, Moeller LC, Samarut J, Wondisford FE, Yen PM, Refetoff S. Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. Endocrinology. 2017 Jul 1;158(7):2052–2057.
Journal cover image

Published In

Endocrinology

DOI

EISSN

1945-7170

Publication Date

July 1, 2017

Volume

158

Issue

7

Start / End Page

2052 / 2057

Location

United States

Related Subject Headings

  • Transcription Factors
  • Thyroid Hormones
  • Terminology as Topic
  • Signal Transduction
  • Receptors, Thyroid Hormone
  • Humans
  • Endocrinology & Metabolism
  • DNA
  • Animals
  • 3202 Clinical sciences