How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.
Journal Article (Journal Article;Review)
An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies in Gram-negative bacteria have shown that the periplasm is isoosmolar with the cytoplasm. Indirect evidence suggests that this is also true for Gram-positive bacteria. In this case the invagination of the septum takes place within the uniformly high osmotic pressure environment, and does not have to fight turgor pressure. A related question is how the V-shaped constriction of Gram-negative bacteria relates to the plate-like septum of Gram-positive bacteria. I collected evidence that Gram-negative bacteria have a latent capability of forming plate-like septa, and present a model in which septal division is the basic mechanism in both Gram-positive and Gram-negative bacteria.
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Duke Authors
Cited Authors
- Erickson, HP
Published Date
- August 2017
Published In
Volume / Issue
- 39 / 8
PubMed ID
- 28699183
Pubmed Central ID
- PMC5569385
Electronic International Standard Serial Number (EISSN)
- 1521-1878
Digital Object Identifier (DOI)
- 10.1002/bies.201700045
Language
- eng
Conference Location
- United States