How bacterial cell division might cheat turgor pressure - a unified mechanism of septal division in Gram-positive and Gram-negative bacteria.

Journal Article (Journal Article;Review)

An important question for bacterial cell division is how the invaginating septum can overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it may not need to. Several studies in Gram-negative bacteria have shown that the periplasm is isoosmolar with the cytoplasm. Indirect evidence suggests that this is also true for Gram-positive bacteria. In this case the invagination of the septum takes place within the uniformly high osmotic pressure environment, and does not have to fight turgor pressure. A related question is how the V-shaped constriction of Gram-negative bacteria relates to the plate-like septum of Gram-positive bacteria. I collected evidence that Gram-negative bacteria have a latent capability of forming plate-like septa, and present a model in which septal division is the basic mechanism in both Gram-positive and Gram-negative bacteria.

Full Text

Duke Authors

Cited Authors

  • Erickson, HP

Published Date

  • August 2017

Published In

Volume / Issue

  • 39 / 8

PubMed ID

  • 28699183

Pubmed Central ID

  • PMC5569385

Electronic International Standard Serial Number (EISSN)

  • 1521-1878

Digital Object Identifier (DOI)

  • 10.1002/bies.201700045

Language

  • eng

Conference Location

  • United States