Identification of a motor-to-auditory pathway important for vocal learning.

Published

Journal Article

Learning to vocalize depends on the ability to adaptively modify the temporal and spectral features of vocal elements. Neurons that convey motor-related signals to the auditory system are theorized to facilitate vocal learning, but the identity and function of such neurons remain unknown. Here we identify a previously unknown neuron type in the songbird brain that transmits vocal motor signals to the auditory cortex. Genetically ablating these neurons in juveniles disrupted their ability to imitate features of an adult tutor's song. Ablating these neurons in adults had little effect on previously learned songs but interfered with their ability to adaptively modify the duration of vocal elements and largely prevented the degradation of songs' temporal features that is normally caused by deafening. These findings identify a motor to auditory circuit essential to vocal imitation and to the adaptive modification of vocal timing.

Full Text

Duke Authors

Cited Authors

  • Roberts, TF; Hisey, E; Tanaka, M; Kearney, MG; Chattree, G; Yang, CF; Shah, NM; Mooney, R

Published Date

  • July 2017

Published In

Volume / Issue

  • 20 / 7

Start / End Page

  • 978 - 986

PubMed ID

  • 28504672

Pubmed Central ID

  • 28504672

Electronic International Standard Serial Number (EISSN)

  • 1546-1726

International Standard Serial Number (ISSN)

  • 1097-6256

Digital Object Identifier (DOI)

  • 10.1038/nn.4563

Language

  • eng