For Embryos, Mother Can Only Take You So Far.

Journal Article (Journal Article)

Early embryonic development is characterized by rapid cleavage divisions, which impose significant constraints on metabolic pathways. In this issue, Song et al. (2017) show that Drosophila embryos synthesize a large fraction of nucleotides on the go and that negative feedback between dATP and ribonucleotide reductase ensures tight control of dNTP concentration.

Full Text

Duke Authors

Cited Authors

  • Ferree, PL; Di Talia, S

Published Date

  • August 7, 2017

Published In

Volume / Issue

  • 42 / 3

Start / End Page

  • 203 - 205

PubMed ID

  • 28787585

Electronic International Standard Serial Number (EISSN)

  • 1878-1551

Digital Object Identifier (DOI)

  • 10.1016/j.devcel.2017.07.016


  • eng

Conference Location

  • United States