Stefano Di Talia | Scholars@Duke

Stefano Di Talia
Assistant Professor of Cell Biology

Current Appointments & Affiliations

Assistant Professor of Cell Biology, Cell Biology, Basic Science Departments 2014
Affiliate of the Regeneration Next Initiative, Regeneration Next Initiative, Institutes and Centers 2016

Contact Information

stefano.ditalia@duke.edu

Background
Education, Training, & Certifications
- Ph.D., Rockefeller University 2009
Duke Appointment History
- Instructor, Temporary in the Department of Cell Biology, Cell Biology, Basic Science Departments 2013 - 2014
Research
Selected Grants
- Time-keeping mechanisms of embryonic cell cycles awarded by National Institutes of Health 2017 - 2022
- Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2022
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Regulation of the Epicardial Injury Response During Heart Regeneration in Zebrafish awarded by National Institutes of Health 2016 - 2019
- An integrative cellular blueprint of vertebrate tissue development awarded by University of California - San Diego 2018 - 2019
- Regulation of Appendage Regeneration in Zebrafish awarded by National Institutes of Health 2006 - 2018
- Time-Keeping Mechanisms in Drosophila Embryonic Development awarded by National Institutes of Health 2014 - 2017
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Cox, BD, De Simone, A, Tornini, VA, Singh, SP, Di Talia, S, and Poss, KD. "In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone." Current Biology : Cb (November 23, 2018). Full Text
  - Deneke, VE, and Di Talia, S. "Chemical waves in cell and developmental biology." The Journal of Cell Biology 217, no. 4 (April 2018): 1193-1204. (Review) Full Text
  - Vergassola, M, Deneke, VE, and Di Talia, S. "Mitotic waves in the early embryogenesis of Drosophila: Bistability traded for speed." Proceedings of the National Academy of Sciences of the United States of America 115, no. 10 (March 2018): E2165-E2174. Full Text
  - Cao, J, Wang, J, Jackman, CP, Cox, AH, Trembley, MA, Balowski, JJ, Cox, BD, De Simone, A, Dickson, AL, Di Talia, S, Small, EM, Kiehart, DP, Bursac, N, and Poss, KD. "Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue." Developmental Cell 42, no. 6 (September 2017): 600-615.e4. Full Text
  - Ferree, PL, and Di Talia, S. "For Embryos, Mother Can Only Take You So Far." Developmental cell 42, no. 3 (August 2017): 203-205. Full Text
  - Tornini, VA, Puliafito, A, Slota, LA, Thompson, JD, Nachtrab, G, Kaushik, A-L, Kapsimali, M, Primo, L, Di Talia, S, and Poss, KD. "Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration." Current Biology : Cb 26, no. 22 (November 10, 2016): 2981-2991. Full Text
  - Di Talia, S, and Poss, KD. "Monitoring Tissue Regeneration at Single-Cell Resolution." Cell stem cell 19, no. 4 (October 2016): 428-431. Full Text
  - Momen-Roknabadi, A, Di Talia, S, and Wieschaus, E. "Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos." Cell reports 16, no. 11 (September 2016): 2793-2801. Full Text
  - Deneke, VE, Melbinger, A, Vergassola, M, and Di Talia, S. "Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos." Developmental Cell 38, no. 4 (August 2016): 399-412. Full Text
  - Ferree, PL, Deneke, VE, and Di Talia, S. "Measuring time during early embryonic development." Seminars in Cell & Developmental Biology 55 (July 2016): 80-88. (Review) Full Text
  - Chen, C-H, Puliafito, A, Cox, BD, Primo, L, Fang, Y, Di Talia, S, and Poss, KD. "Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish." Developmental Cell 36, no. 6 (March 2016): 668-680. Full Text
  - Xenopoulos, P, Kang, M, Puliafito, A, Di Talia, S, and Hadjantonakis, A-K. "Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst." Cell Reports (March 4, 2015). Full Text
  - Di Talia, S, and Wieschaus, EF. "Simple biochemical pathways far from steady state can provide switchlike and integrated responses." Biophysical journal 107, no. 3 (August 2014): L1-L4. Full Text
  - Schrode, N, Saiz, N, Di Talia, S, and Hadjantonakis, A-K. "GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst." Developmental Cell 29, no. 4 (May 15, 2014): 454-467. Full Text
  - Di Talia, S, She, R, Blythe, SA, Lu, X, Zhang, QF, and Wieschaus, EF. "Posttranslational Control of Cdc25 Degradation Terminates Drosophila's Early Cell-Cycle Program." CURRENT BIOLOGY 23, no. 2 (January 21, 2013): 127-132. Full Text Link to Item
  - Di Talia, S, and Wieschaus, EF. "Short-Term Integration of Cdc25 Dynamics Controls Mitotic Entry during Drosophila Gastrulation." DEVELOPMENTAL CELL 22, no. 4 (April 17, 2012): 763-774. Full Text Link to Item
  - Zilman, A, Di Talia, S, Jovanovic-Talisman, T, Chait, BT, Rout, MP, and Magnasco, MO. "Enhancement of transport selectivity through nano-channels by non-specific competition." Plos Computational Biology 6, no. 6 (June 10, 2010): e1000804-null. Full Text
  - Zilman, A, Talia, SD, Jovanovic-Talisman, T, Chait, BT, Rout, MP, and Magnasco, MO. "Enhancement of transport selectivity through nano-channels by non-specific competition." PLoS computational biology 6, no. 6 (2010): e1000804-. Full Text
  - Di Talia, S, Wang, H, Skotheim, JM, Rosebrock, AP, Futcher, B, and Cross, FR. "Daughter-Specific Transcription Factors Regulate Cell Size Control in Budding Yeast." PLOS BIOLOGY 7, no. 10 (October 2009). Full Text Link to Item
  - Skotheim, JM, Di Talia, S, Siggia, ED, and Cross, FR. "Positive feedback of G1 cyclins ensures coherent cell cycle entry." Nature 454, no. 7202 (July 2008): 291-296. Full Text
  - Di Talia, S, Skotheim, JM, Bean, JM, Siggia, ED, and Cross, FR. "The effects of molecular noise and size control on variability in the budding yeast cell cycle (vol 448, pg 947, 2007)." NATURE 450, no. 7173 (December 20, 2007): 1272-1272. Full Text Link to Item
  - Di Talia, S, Skotheim, JM, Bean, JM, Siggia, ED, and Cross, FR. "The effects of molecular noise and size control on variability in the budding yeast cell cycle." Nature 448, no. 7156 (August 2007): 947-951. Full Text
  - Zilman, A, Di Talia, S, Chait, BT, Rout, MP, and Magnasco, MO. "Efficiency, selectivity, and robustness of nucleocytoplasmic transport." Plos Computational Biology 3, no. 7 (July 2007): e125-null. Full Text
  - de Candia, A, Gamba, A, Cavalli, F, Coniglio, A, Di Talia, S, Bussolino, F, and Serini, G. "A simulation environment for directional sensing as a phase separation process. (Published online)" Sci STKE 2007, no. 378 (March 20, 2007): pl1-. Full Text Link to Item
  - Zilman, A, Talia, SD, Chait, BT, Rout, MP, and Magnasco, MO. "Efficiency, selectivity, and robustness of nucleocytoplasmic transport." PLoS computational biology 3, no. 7 (2007): e125-. Full Text
  - Di Talia, S, Gamba, A, Lamberti, F, and Serini, G. "Role of repulsive factors in vascularization dynamics." PHYSICAL REVIEW E 73, no. 4 (April 2006). Full Text Link to Item
  - Di Talia, S, Gamba, A, Lamberti, F, and Serini, G. "Role of repulsive factors in vascularization dynamics." Phys Rev E Stat Nonlin Soft Matter Phys 73, no. 4 Pt 1 (April 2006): 041917-. Full Text Link to Item
  - Gamba, A, de Candia, A, Di Talia, S, Coniglio, A, Bussolino, F, and Serini, G. "Diffusion-limited phase separation in eukaryotic chemotaxis." Proceedings of the National Academy of Sciences of the United States of America 102, no. 47 (November 16, 2005): 16927-16932. Full Text
  - Coniglio, A, de Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation (vol 69, art no 051910, 2004)." PHYSICAL REVIEW E 70, no. 3 (September 2004). Full Text Link to Item
  - Coniglio, A, De Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation." Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 69, no. 5 2 (May 1, 2004).
  - Coniglio, A, de Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation." PHYSICAL REVIEW E 69, no. 5 (May 2004). Full Text Link to Item
  - Coniglio, A, de Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation." Phys Rev E Stat Nonlin Soft Matter Phys 69, no. 5 Pt 1 (May 2004): 051910-. Full Text Link to Item
  - Gamba, A, Ambrosi, D, Coniglio, A, de Candia, A, Di Talia, S, Giraudo, E, Serini, G, Preziosi, L, and Bussolino, F. "Percolation, morphogenesis, and burgers dynamics in blood vessels formation." Physical Review Letters 90, no. 11 (March 17, 2003): 118101-null. Full Text
  - Ferree, PL, and Di Talia, S. "Chemical Waves in Embryonic Cell Cycles(Published online)." Israel Journal of Chemistry . Full Text
- Conference Papers
  - Deneke, V, Vergassola, M, Puliafito, A, and Di Talia, S. "Physical and molecular mechanisms of cell cycle synchronization in early Drosophila embryos." Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO). Philadelphia, PA. December 2, 2017 - December 6, 2017.: AMER SOC CELL BIOLOGY, January 1, 2017. Link to Item
  - Falahati, H, Di Talia, S, and Wieschaus, E. "Temperature-induced uncoupling of cell cycle regulatory mechanisms." Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO). Philadelphia, PA. December 2, 2017 - December 6, 2017.: AMER SOC CELL BIOLOGY, January 1, 2017. Link to Item
  - Saiz, N, Kang, M, Puliafito, A, Schrode, N, Xenopoulos, P, Lou, X, Di Talia, S, and Hadjantonakis, AK. "Quantitative analyses for elucidating mechanisms of cell fate commitment in the mouse blastocyst." January 1, 2015. Full Text
  - Roknabadi, AM, Di Talia, S, and Wieschaus, E. "Studying The Regulation of Temporal Patterning of String Transcription in Early Drosophila Cell Cycles." December 2014. Link to Item
  - Gamba, A, de Candia, A, Cavalli, F, Di Talia, S, Coniglio, A, Bussolino, F, and Serini, G. "A computational model for eukaryotic directional sensing." 2006. Link to Item
  - Gamba, A, Candia, AD, Talia, SD, Coniglio, A, Bussolino, F, and Serini, G. "Phase Separation in Eukaryotic Directional Sensing." : Birkhäuser Boston,. Full Text
Teaching & Mentoring
Recent Courses

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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses