Stefano Di Talia | Scholars@Duke

Stefano Di Talia
Assistant Professor of Cell Biology

Current Appointments & Affiliations

Assistant Professor of Cell Biology, Cell Biology, Basic Science Departments 2014
Affiliate of the Regeneration Next Initiative, Regeneration Next Initiative, Institutes and Centers 2016

Contact Information

stefano.ditalia@duke.edu

Background
Education, Training, & Certifications
- Ph.D., Rockefeller University 2009
Duke Appointment History
- Instructor, Temporary in the Department of Cell Biology, Cell Biology, Basic Science Departments 2013 - 2014
Research
Selected Grants
- Time-keeping mechanisms of embryonic cell cycles awarded by National Institutes of Health 2017 - 2022
- Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2022
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Regulation of the Epicardial Injury Response During Heart Regeneration in Zebrafish awarded by National Institutes of Health 2016 - 2019
- An integrative cellular blueprint of vertebrate tissue development awarded by University of California - San Diego 2018 - 2019
- Regulation of Appendage Regeneration in Zebrafish awarded by National Institutes of Health 2006 - 2018
- Time-Keeping Mechanisms in Drosophila Embryonic Development awarded by National Institutes of Health 2014 - 2017
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Cox, BD, De Simone, A, Tornini, VA, Singh, SP, Di Talia, S, and Poss, KD. "In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone." Current Biology : Cb 28, no. 24 (December 2018): 3937-3947.e4. Full Text
  - Ferree, PL, and Di Talia, S. "Chemical Waves in Embryonic Cell Cycles." Israel Journal of Chemistry 58, no. 6-7 (June 2018): 714-721. Full Text
  - Deneke, VE, and Di Talia, S. "Chemical waves in cell and developmental biology." The Journal of Cell Biology 217, no. 4 (April 2018): 1193-1204. (Review) Full Text
  - Vergassola, M, Deneke, VE, and Di Talia, S. "Mitotic waves in the early embryogenesis of Drosophila: Bistability traded for speed." Proceedings of the National Academy of Sciences of the United States of America 115, no. 10 (March 2018): E2165-E2174. Full Text
  - Cao, J, Wang, J, Jackman, CP, Cox, AH, Trembley, MA, Balowski, JJ, Cox, BD, De Simone, A, Dickson, AL, Di Talia, S, Small, EM, Kiehart, DP, Bursac, N, and Poss, KD. "Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue." Developmental Cell 42, no. 6 (September 2017): 600-615.e4. Full Text
  - Ferree, PL, and Di Talia, S. "For Embryos, Mother Can Only Take You So Far." Developmental cell 42, no. 3 (August 2017): 203-205. Full Text
  - Tornini, VA, Puliafito, A, Slota, LA, Thompson, JD, Nachtrab, G, Kaushik, A-L, Kapsimali, M, Primo, L, Di Talia, S, and Poss, KD. "Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration." Current Biology : Cb 26, no. 22 (November 10, 2016): 2981-2991. Full Text
  - Di Talia, S, and Poss, KD. "Monitoring Tissue Regeneration at Single-Cell Resolution." Cell stem cell 19, no. 4 (October 2016): 428-431. Full Text
  - Momen-Roknabadi, A, Di Talia, S, and Wieschaus, E. "Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos." Cell reports 16, no. 11 (September 2016): 2793-2801. Full Text
  - Deneke, VE, Melbinger, A, Vergassola, M, and Di Talia, S. "Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos." Developmental Cell 38, no. 4 (August 2016): 399-412. Full Text
  - Ferree, PL, Deneke, VE, and Di Talia, S. "Measuring time during early embryonic development." Seminars in Cell & Developmental Biology 55 (July 2016): 80-88. (Review) Full Text
  - Chen, C-H, Puliafito, A, Cox, BD, Primo, L, Fang, Y, Di Talia, S, and Poss, KD. "Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish." Developmental Cell 36, no. 6 (March 2016): 668-680. Full Text
  - Xenopoulos, P, Kang, M, Puliafito, A, Di Talia, S, and Hadjantonakis, A-K. "Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst." Cell Reports (March 4, 2015). Full Text
  - Di Talia, S, and Wieschaus, EF. "Simple biochemical pathways far from steady state can provide switchlike and integrated responses." Biophysical journal 107, no. 3 (August 2014): L1-L4. Full Text
  - Schrode, N, Saiz, N, Di Talia, S, and Hadjantonakis, A-K. "GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst." Developmental Cell 29, no. 4 (May 15, 2014): 454-467. Full Text
  - Di Talia, S, She, R, Blythe, SA, Lu, X, Zhang, QF, and Wieschaus, EF. "Posttranslational Control of Cdc25 Degradation Terminates Drosophila's Early Cell-Cycle Program." CURRENT BIOLOGY 23, no. 2 (January 21, 2013): 127-132. Full Text Link to Item
  - Di Talia, S, and Wieschaus, EF. "Short-Term Integration of Cdc25 Dynamics Controls Mitotic Entry during Drosophila Gastrulation." DEVELOPMENTAL CELL 22, no. 4 (April 17, 2012): 763-774. Full Text Link to Item
  - Zilman, A, Di Talia, S, Jovanovic-Talisman, T, Chait, BT, Rout, MP, and Magnasco, MO. "Enhancement of transport selectivity through nano-channels by non-specific competition." Plos Computational Biology 6, no. 6 (June 10, 2010): e1000804-null. Full Text
  - Zilman, A, Talia, SD, Jovanovic-Talisman, T, Chait, BT, Rout, MP, and Magnasco, MO. "Enhancement of transport selectivity through nano-channels by non-specific competition." PLoS computational biology 6, no. 6 (2010): e1000804-. Full Text
  - Di Talia, S, Wang, H, Skotheim, JM, Rosebrock, AP, Futcher, B, and Cross, FR. "Daughter-Specific Transcription Factors Regulate Cell Size Control in Budding Yeast." PLOS BIOLOGY 7, no. 10 (October 2009). Full Text Link to Item
  - Skotheim, JM, Di Talia, S, Siggia, ED, and Cross, FR. "Positive feedback of G1 cyclins ensures coherent cell cycle entry." Nature 454, no. 7202 (July 2008): 291-296. Full Text
  - Di Talia, S, Skotheim, JM, Bean, JM, Siggia, ED, and Cross, FR. "The effects of molecular noise and size control on variability in the budding yeast cell cycle (Nature (2007) 448, (947-951))." Nature 450, no. 7173 (December 20, 2007): 1272-null. Full Text
  - Di Talia, S, Skotheim, JM, Bean, JM, Siggia, ED, and Cross, FR. "The effects of molecular noise and size control on variability in the budding yeast cell cycle." Nature 448, no. 7156 (August 2007): 947-951. Full Text
  - Zilman, A, Di Talia, S, Chait, BT, Rout, MP, and Magnasco, MO. "Efficiency, selectivity, and robustness of nucleocytoplasmic transport." Plos Computational Biology 3, no. 7 (July 2007): e125-null. Full Text
  - de Candia, A, Gamba, A, Cavalli, F, Coniglio, A, Di Talia, S, Bussolino, F, and Serini, G. "A simulation environment for directional sensing as a phase separation process. (Published online)" Sci STKE 2007, no. 378 (March 20, 2007): pl1-. Full Text Link to Item
  - Zilman, A, Talia, SD, Chait, BT, Rout, MP, and Magnasco, MO. "Efficiency, selectivity, and robustness of nucleocytoplasmic transport." PLoS computational biology 3, no. 7 (2007): e125-. Full Text
  - Di Talia, S, Gamba, A, Lamberti, F, and Serini, G. "Role of repulsive factors in vascularization dynamics." Physical Review E Statistical, Nonlinear, and Soft Matter Physics 73, no. 4 (April 21, 2006). Full Text
  - Di Talia, S, Gamba, A, Lamberti, F, and Serini, G. "Role of repulsive factors in vascularization dynamics." Phys Rev E Stat Nonlin Soft Matter Phys 73, no. 4 Pt 1 (April 2006): 041917-. Full Text Link to Item
  - Gamba, A, de Candia, A, Di Talia, S, Coniglio, A, Bussolino, F, and Serini, G. "Diffusion-limited phase separation in eukaryotic chemotaxis." Proceedings of the National Academy of Sciences of the United States of America 102, no. 47 (November 16, 2005): 16927-16932. Full Text
  - Coniglio, A, De Candia, A, Di Talia, S, and Gamba, A. "Erratum: Percolation and Burgers' dynamics in a model of capillary formation (Physical Review E (2004) 69 (051910))." Physical Review E Statistical, Nonlinear, and Soft Matter Physics 70, no. 3 2 (September 1, 2004): 039902-039901. Full Text
  - Coniglio, A, de Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation." Phys Rev E Stat Nonlin Soft Matter Phys 69, no. 5 Pt 1 (May 2004): 051910-. Full Text Link to Item
  - Coniglio, A, De Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers' dynamics in a model of capillary formation." Physical Review E Statistical, Nonlinear, and Soft Matter Physics 69, no. 5 2 (January 1, 2004).
  - Coniglio, A, de Candia, A, Di Talia, S, and Gamba, A. "Percolation and Burgers’ dynamics in a model of capillary formation." Physical Review E Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics 69, no. 5 (January 1, 2004): 10-null. Full Text
  - Gamba, A, Ambrosi, D, Coniglio, A, de Candia, A, Di Talia, S, Giraudo, E, Serini, G, Preziosi, L, and Bussolino, F. "Percolation, morphogenesis, and burgers dynamics in blood vessels formation." Physical Review Letters 90, no. 11 (March 17, 2003): 118101-null. Full Text
- Conference Papers
  - Deneke, V, Vergassola, M, Puliafito, A, and Di Talia, S. "Physical and molecular mechanisms of cell cycle synchronization in early Drosophila embryos." Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO). Philadelphia, PA. December 2, 2017 - December 6, 2017.: AMER SOC CELL BIOLOGY, January 1, 2017. Link to Item
  - Falahati, H, Di Talia, S, and Wieschaus, E. "Temperature-induced uncoupling of cell cycle regulatory mechanisms." Annual Joint Meeting of the American-Society-for-Cell-Biology and the European-Molecular-Biology-Organization (ASCB/EMBO). Philadelphia, PA. December 2, 2017 - December 6, 2017.: AMER SOC CELL BIOLOGY, January 1, 2017. Link to Item
  - Saiz, N, Kang, M, Puliafito, A, Schrode, N, Xenopoulos, P, Lou, X, Di Talia, S, and Hadjantonakis, AK. "Quantitative analyses for elucidating mechanisms of cell fate commitment in the mouse blastocyst." January 1, 2015. Full Text
  - Roknabadi, AM, Di Talia, S, and Wieschaus, E. "Studying The Regulation of Temporal Patterning of String Transcription in Early Drosophila Cell Cycles." December 2014. Link to Item
  - Gamba, A, De Candia, A, Di Talia, S, Coniglio, A, Bussolino, F, and Serini, G. "Phase separation in eukaryotic directional sensing." January 1, 2007. Full Text
  - Gamba, A, De Candia, A, Cavalli, F, Di Talia, S, Coniglio, A, Bussolino, F, and Serini, G. "A computational model for eukaryotic directional sensing." January 1, 2006.
Teaching & Mentoring
Recent Courses

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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses