Spatial tuning of negative and positive Poisson's ratio in a multi-layer scaffold.

Journal Article (Journal Article)

While elastic modulus is tunable in tissue engineering scaffolds, it is substantially more challenging to tune the Poisson's ratio of scaffolds. In certain biological applications, scaffolds with a tunable Poisson's ratio may be more suitable for emulating the behavior of native tissue mechanics. Here, we design and fabricate a scaffold, which exhibits simultaneous negative and positive Poisson's ratio behavior. Custom-made digital micro-mirror device stereolithography was used to fabricate single- and multiple-layer scaffolds using polyethylene glycol-based biomaterial. These scaffolds are composed of pore structures having special geometries, and deformation mechanisms, which can be tuned to exhibit both negative Poisson's ratio (NPR) and positive Poisson's ratio (PPR) behavior in a side-to-side or top-to-bottom configuration. Strain measurement results demonstrate that analytical deformation models and simulations accurately predict the Poisson's ratios of both the NPR and PPR regions. This hybrid Poisson's ratio property can be imparted to any photocurable material, and potentially be applicable in a variety of biomedical applications.

Full Text

Duke Authors

Cited Authors

  • Soman, P; Lee, JW; Phadke, A; Varghese, S; Chen, S

Published Date

  • July 2012

Published In

Volume / Issue

  • 8 / 7

Start / End Page

  • 2587 - 2594

PubMed ID

  • 22465577

Pubmed Central ID

  • PMC3409644

Electronic International Standard Serial Number (EISSN)

  • 1878-7568

Digital Object Identifier (DOI)

  • 10.1016/j.actbio.2012.03.035


  • eng

Conference Location

  • England