Chronic Osteomyelitis of the Distal Femur Treated with Resection and Delayed Endoprosthetic Reconstruction: A Report of Three Cases.

Journal Article

Chronic osteomyelitis involving the distal femur often results in amputation or arthrodesis. This article presents three cases of chronic osteomyelitis treated with a staged approach culminating in endoprosthetic reconstruction. Stage one involved resection of infected bone and placement of an intramedullary nail spanning the bony defect between proximal femur and tibia, with antibiotic cement packed around the nail. Patients were then placed on long-term IV +/- oral antibiotics to clear the infection. A "cooldown" period was then used between stages where patients were off antibiotics and inflammatory markers were monitored for signs of remaining infection. Stage two then involved reconstruction of the distal femur and knee with an endoprosthesis. In the appropriate patient, this treatment strategy offers another option in this challenging population.

Full Text

Duke Authors

Cited Authors

  • Ryan, S; Eward, W; Brigman, B; Zura, R

Published Date

  • 2017

Published In

Volume / Issue

  • 2017 /

Start / End Page

  • 5141032 -

PubMed ID

  • 28894615

Pubmed Central ID

  • PMC5574225

International Standard Serial Number (ISSN)

  • 2090-6749

Digital Object Identifier (DOI)

  • 10.1155/2017/5141032


  • eng

Conference Location

  • United States