Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors


Journal Article

This paper presents the development and application of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene. © 1988 SPIE.

Full Text

Duke Authors

Cited Authors

  • Vo-Dinh, T; Tromberg, BJ; Griffin, GD; Ambrose, KR; Sepaniak, MJ; Santella, RM

Published Date

  • April 27, 1988

Published In

Volume / Issue

  • 910 /

Start / End Page

  • 87 - 94

Electronic International Standard Serial Number (EISSN)

  • 1996-756X

International Standard Serial Number (ISSN)

  • 0277-786X

Digital Object Identifier (DOI)

  • 10.1117/12.945444

Citation Source

  • Scopus