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Immunofluorescence detection for fiber optics chemical and biological sensors

Publication ,  Journal Article
Vo-Dinn, T; Tromberg, BJ; Sepaniak, MJ; Griffin, GD; Ambrose, KR; Santella, RM
Published in: Proceedings of SPIE the International Society for Optical Engineering
April 27, 1988

This paper presents the development and application of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene.

Duke Scholars

Published In

Proceedings of SPIE the International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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ICMJE
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Vo-Dinn, T., Tromberg, B. J., Sepaniak, M. J., Griffin, G. D., Ambrose, K. R., & Santella, R. M. (1988). Immunofluorescence detection for fiber optics chemical and biological sensors. Proceedings of SPIE the International Society for Optical Engineering, 910, 87–94. https://doi.org/10.1117/12.945444
Vo-Dinn, T., B. J. Tromberg, M. J. Sepaniak, G. D. Griffin, K. R. Ambrose, and R. M. Santella. “Immunofluorescence detection for fiber optics chemical and biological sensors.” Proceedings of SPIE the International Society for Optical Engineering 910 (April 27, 1988): 87–94. https://doi.org/10.1117/12.945444.
Vo-Dinn T, Tromberg BJ, Sepaniak MJ, Griffin GD, Ambrose KR, Santella RM. Immunofluorescence detection for fiber optics chemical and biological sensors. Proceedings of SPIE the International Society for Optical Engineering. 1988 Apr 27;910:87–94.
Vo-Dinn, T., et al. “Immunofluorescence detection for fiber optics chemical and biological sensors.” Proceedings of SPIE the International Society for Optical Engineering, vol. 910, Apr. 1988, pp. 87–94. Scopus, doi:10.1117/12.945444.
Vo-Dinn T, Tromberg BJ, Sepaniak MJ, Griffin GD, Ambrose KR, Santella RM. Immunofluorescence detection for fiber optics chemical and biological sensors. Proceedings of SPIE the International Society for Optical Engineering. 1988 Apr 27;910:87–94.

Published In

Proceedings of SPIE the International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering