B-cell targeting in chronic graft-versus-host disease.
Journal Article (Journal Article;Review)
Over the last decade, our understanding of the pathophysiology of chronic graft-versus-host disease (cGVHD) has improved considerably. In this spotlight, we discuss emerging insights into the pathophysiology of cGVHD with a focus on B cells. First, we summarize supporting evidence derived from mouse and human studies. Next, novel cGVHD therapy approaches that target B cells will be covered to provide treating physicians with an overview of the rationale behind the emerging armamentarium against cGVHD.
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Duke Authors
Cited Authors
- Zeiser, R; Sarantopoulos, S; Blazar, BR
Published Date
- March 29, 2018
Published In
Volume / Issue
- 131 / 13
Start / End Page
- 1399 - 1405
PubMed ID
- 29437591
Pubmed Central ID
- PMC6031308
Electronic International Standard Serial Number (EISSN)
- 1528-0020
Digital Object Identifier (DOI)
- 10.1182/blood-2017-11-784017
Language
- eng
Conference Location
- United States