Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship, Hematology/ Oncology, Dana-Farber Cancer Institute 2002 - 2005
  • Chief Resident, Internal Medicine, Boston University School of Medicine 2001 - 2002
  • Resident, Internal Medicine, Boston University School of Medicine 1999 - 2001
  • Intern, Internal Medicine, Boston University School of Medicine 1998 - 1999
  • M.D., Boston University 1998
  • Ph.D., Boston University School of Medicine 1998
• 

  Duke Appointment History

  • Assistant Professor of Immunology, Immunology, Basic Science Departments 2015 - 2018
  • Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2015 - 2018
  • Assistant Research Professor in the Department of Immunology, Immunology, Basic Science Departments 2015
  • Associate Professor of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2015
  • Instructor, Temporary in the Department of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2013 - 2015
• 

  Leadership & Clinical Positions at Duke

  • Head of Duke GVHD Multi-disciplinary ResearchCare Team
    MSTP admissions committee
    Hem/Onc Fellowship admissions committee
    Co-chair Duke Scholars in Molecular Medicine (Oncology)
• 

  Academic Positions Outside Duke

  • Vice Chair ASH Scholar Award Review, The American Society of Hematology (ASH). 2018 - 2021
  • Director of Laboratory Sciences, American Society of Bone Marrow Transplantation. 2018 - 2023
  • Inductee, American Society of Clinical Investigation. 2017 - 2119
• Research
• 

  Selected Grants

  • Basic Immunology Training Program awarded by National Institutes of Health 2020 - 2025
  • Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2022
  • Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
  • Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD awarded by National Institutes of Health 2015 - 2021
  • Transfusion Medicine and Hematology awarded by National Institutes of Health 1975 - 2021
  • Breaking B-Cell Tolerance to Produce Antibodies that Eradicate Leukemias and Lymphomas awarded by Department of Defense 2018 - 2020
  • UNC - Duke Immunotherapy Training Program awarded by University of North Carolina - Chapel Hill 2019 - 2020
  • The Notch2-BCR Axis: Targeting Drivers of B cell Fate in Chronic GVHD awarded by Leukemia & Lymphoma Society 2015 - 2019
  • Understanding Aberrant TLR7 Signaling in B Cells from Patients with Chronic GVHD awarded by American Society for Blood and Marrow Transplantation 2018 - 2019
  • A Phase II of Entospletinib, a SYK Inhibitor, First line cGVHD patients awarded by Gilead Sciences, Inc. 2016 - 2019
  • The Effects of Syk Blockade with GS-9973 on Immunity in a Murine Model of GVHD awarded by Gilead Sciences, Inc. 2016 - 2018
  • Improving Outcomes Assessment in cGVHD awarded by Fred Hutchinson Cancer Research Center 2015 - 2018
  • BAFF-Driven Targeted Immunotherapy for Patients with Leukemia awarded by Department of Defense 2011 - 2015
  • BAFF Pathology: Novel Therapeutic Targets in Chronic Graft versus Host Disease awarded by National Institutes of Health 2011 - 2015
• 

  Fellowships, Supported Research, & Other Grants

  • ASBMT Young Investigator Award awarded by American Society of Bone Marrow Transplantation 2018
  • T32 Immunotherapy Duke-UNC awarded by NIH 2018
  • Duke Scholar Award awarded by Duke University 2017
• 

  External Relationships

  • Grant from the European Commission in collaobation with INserm/Bordeaux Univ in France, Dr. Jonathan Visentin, has been awarded and is pending;
  • Moffit Cancer Center
  • NIH/NCI, working on consensus criteria for chronic GVHD (Steve Pavletic lead at NCI)
  • Rigel Pharmaceuticals Inc advisory board Jan 2020 and now signed consulting contract; Rigel also supplies the drug, fostamatinib (also called TAvalese) for our NIH-funded Duke clinical trial
  • TG Therapeutics, IC, New York NY
  • The American Society of Hematology (ASH)
  • University of Los Angeles
  • Vanderbilt University
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplant, July 5, 2020. https://doi.org/10.1038/s41409-020-0991-5.
       Full Text  Link to Item
    • Sullivan, Keith M., and Stefanie Sarantopoulos. “Allogeneic HSCT for autoimmune disease: a shared decision.” Nat Rev Rheumatol 15, no. 12 (December 2019): 701–2. https://doi.org/10.1038/s41584-019-0306-7.
       Full Text  Link to Item
    • Cardones, Adela R., Keith M. Sullivan, Cindy Green, Nelson J. Chao, Krista Rowe-Nichols, Lionel L. Bañez, Claude S. Burton, et al. “Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease.” Jama Dermatol 155, no. 7 (July 1, 2019): 833–37. https://doi.org/10.1001/jamadermatol.2018.5459.
       Full Text  Link to Item
    • McManigle, William, Ayman Youssef, and Stefanie Sarantopoulos. “B cells in chronic graft-versus-host disease.” Hum Immunol 80, no. 6 (June 2019): 393–99. https://doi.org/10.1016/j.humimm.2019.03.003.
       Full Text  Link to Item
    • Cohen, Jeffrey A., Laura E. Baldassari, Harold L. Atkins, James D. Bowen, Christopher Bredeson, Paul A. Carpenter, John R. Corboy, et al. “Autologous Hematopoietic Cell Transplantation for Treatment-Refractory Relapsing Multiple Sclerosis: Position Statement from the American Society for Blood and Marrow Transplantation.” Biol Blood Marrow Transplant 25, no. 5 (May 2019): 845–54. https://doi.org/10.1016/j.bbmt.2019.02.014.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Adela R. Cardones, and Keith M. Sullivan. “How I treat refractory chronic graft-versus-host disease.” Blood 133, no. 11 (March 14, 2019): 1191–1200. https://doi.org/10.1182/blood-2018-04-785899.
       Full Text  Link to Item
    • Radojcic, Vedran, Katelyn Paz, Jooho Chung, Jing Du, Eric T. Perkey, Ryan Flynn, Sanja Ivcevic, et al. “Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.” Blood 132, no. 20 (November 15, 2018): 2188–2200. https://doi.org/10.1182/blood-2018-03-841155.
       Full Text  Open Access Copy  Link to Item
    • Carpenter, Paul A., Brent R. Logan, Stephanie J. Lee, Daniel J. Weisdorf, Laura Johnston, Luciano J. Costa, Carrie L. Kitko, et al. “A phase II/III randomized, multicenter trial of prednisone/sirolimus versus prednisone/ sirolimus/calcineurin inhibitor for the treatment of chronic graft-versus-host disease: BMT CTN 0801.” Haematologica 103, no. 11 (November 2018): 1915–24. https://doi.org/10.3324/haematol.2018.195123.
       Full Text  Link to Item
    • Poe, Jonathan C., Wei Jia, Julie A. Di Paolo, Nancy J. Reyes, Ji Yun Kim, Hsuan Su, John S. Sundy, et al. “SYK inhibitor entospletinib prevents ocular and skin GVHD in mice.” Jci Insight 3, no. 19 (October 4, 2018). https://doi.org/10.1172/jci.insight.122430.
       Full Text  Link to Item
    • Sullivan, Keith M., Navneet S. Majhail, Christopher Bredeson, Paul A. Carpenter, Soumya Chatterjee, Leslie J. Crofford, George E. Georges, et al. “Systemic Sclerosis as an Indication for Autologous Hematopoietic Cell Transplantation: Position Statement from the American Society for Blood and Marrow Transplantation.” Biol Blood Marrow Transplant 24, no. 10 (October 2018): 1961–64. https://doi.org/10.1016/j.bbmt.2018.06.025.
       Full Text  Open Access Copy  Link to Item
    • Kolupaev, Oleg V., Trisha A. Dant, Hemamalini Bommiasamy, Danny W. Bruce, Kenneth A. Fowler, Stephen L. Tilley, Karen P. McKinnon, et al. “Impaired bone marrow B-cell development in mice with a bronchiolitis obliterans model of cGVHD.” Blood Adv 2, no. 18 (September 25, 2018): 2307–19. https://doi.org/10.1182/bloodadvances.2017014977.
       Full Text  Open Access Copy  Link to Item
    • Chronic GVHD Consortium, M. G. “Design and Patient Characteristics of the Chronic Graft-versus-Host Disease Response Measures Validation Study.” Biol Blood Marrow Transplant 24, no. 8 (August 2018): 1727–32. https://doi.org/10.1016/j.bbmt.2018.02.010.
       Full Text  Link to Item
    • Wolff, D., H. Greinix, S. J. Lee, T. Gooley, S. Paczesny, S. Pavletic, F. Hakim, et al. “Biomarkers in chronic graft-versus-host disease: quo vadis?” Bone Marrow Transplant 53, no. 7 (July 2018): 832–37. https://doi.org/10.1038/s41409-018-0092-x.
       Full Text  Link to Item
    • Zeiser, Robert, Stefanie Sarantopoulos, and Bruce R. Blazar. “B-cell targeting in chronic graft-versus-host disease.” Blood 131, no. 13 (March 29, 2018): 1399–1405. https://doi.org/10.1182/blood-2017-11-784017.
       Full Text  Open Access Copy  Link to Item
    • Anand, Sarah, and Stefanie Sarantopoulos. “Chronic Graft-versus-Host Disease: A Long Road Ahead.” Biol Blood Marrow Transplant 24, no. 3 (March 2018): 423–24. https://doi.org/10.1016/j.bbmt.2018.01.010.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie. “Allogeneic Stem-Cell Transplantation - A T-Cell Balancing ACT.” N Engl J Med 378, no. 5 (February 1, 2018): 480–82. https://doi.org/10.1056/NEJMcibr1713238.
       Full Text  Link to Item
    • Poe, Jonathan C., Wei Jia, Hsuan Su, Sarah Anand, Jeremy J. Rose, Prasanthi V. Tata, Amy N. Suthers, et al. “An aberrant NOTCH2-BCR signaling axis in B cells from patients with chronic GVHD.” Blood 130, no. 19 (November 9, 2017): 2131–45. https://doi.org/10.1182/blood-2017-05-782466.
       Full Text  Link to Item
    • Anand, Sarah, Samantha Thomas, Terry Hyslop, Janet Adcock, Kelly Corbet, Cristina Gasparetto, Richard Lopez, et al. “Transplantation of Ex Vivo Expanded Umbilical Cord Blood (NiCord) Decreases Early Infection and Hospitalization.” Biol Blood Marrow Transplant 23, no. 7 (July 2017): 1151–57. https://doi.org/10.1016/j.bbmt.2017.04.001.
       Full Text  Link to Item
    • Saliba, R. M., S. Sarantopoulos, C. L. Kitko, A. Pawarode, S. C. Goldstein, J. Magenau, A. M. Alousi, et al. “B-cell activating factor (BAFF) plasma level at the time of chronic GvHD diagnosis is a potential predictor of non-relapse mortality.” Bone Marrow Transplant 52, no. 7 (July 2017): 1010–15. https://doi.org/10.1038/bmt.2017.73.
       Full Text  Link to Item
    • Gea-Banacloche, Juan, Krishna V. Komanduri, Paul Carpenter, Sophie Paczesny, Stefanie Sarantopoulos, Jo-Anne Young, Nahed El Kassar, et al. “National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Immune Dysregulation and Pathobiology Working Group Report.” Biol Blood Marrow Transplant 23, no. 6 (June 2017): 870–81. https://doi.org/10.1016/j.bbmt.2016.10.001.
       Full Text  Link to Item
    • Cooke, Kenneth R., Leo Luznik, Stefanie Sarantopoulos, Frances T. Hakim, Madan Jagasia, Daniel H. Fowler, Marcel R. M. van den Brink, et al. “The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 211–34. https://doi.org/10.1016/j.bbmt.2016.09.023.
       Full Text  Link to Item
    • Sivaraj, Dharshan, Michael M. Green, Zhiguo Li, Anthony D. Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D. Long, et al. “Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma.” Biol Blood Marrow Transplant 23, no. 2 (February 2017): 262–68. https://doi.org/10.1016/j.bbmt.2016.11.010.
       Full Text  Link to Item
    • Suthers, Amy N., and Stefanie Sarantopoulos. “TLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells.” Front Immunol 8 (2017): 775. https://doi.org/10.3389/fimmu.2017.00775.
       Full Text  Link to Item
    • Sullivan, Keith M., Ankoor Shah, Stefanie Sarantopoulos, and Daniel E. Furst. “Review: Hematopoietic Stem Cell Transplantation for Scleroderma: Effective Immunomodulatory Therapy for Patients With Pulmonary Involvement.” Arthritis Rheumatol 68, no. 10 (October 2016): 2361–71. https://doi.org/10.1002/art.39748.
       Full Text  Open Access Copy  Link to Item
    • Green, Michael M. B., Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, et al. “Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.” J Hematol Oncol 9, no. 1 (August 17, 2016): 71. https://doi.org/10.1186/s13045-016-0301-2.
       Full Text  Open Access Copy  Link to Item
    • Yang, Yang, Jonathan C. Poe, Lisong Yang, Andrew Fedoriw, Siddhi Desai, Terry Magnuson, Zhiguo Li, et al. “Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo.” Nucleic Acids Res 44, no. 9 (May 19, 2016): 4174–88. https://doi.org/10.1093/nar/gkw072.
       Full Text  Open Access Copy  Link to Item
    • Sarantopoulos, Stefanie. “Antibodies are back for thymic attack in cGVHD.” Blood 127, no. 18 (May 5, 2016): 2170–71. https://doi.org/10.1182/blood-2016-03-701706.
       Full Text  Open Access Copy  Link to Item
    • DeFilipp, Z., M. Purcell, W. A. C. Harris, D. J. Chandra, C. Gleason, J. Wrammert, S. Sarantopoulos, and E. K. Waller. “Monitoring the kinetics of B-cell recovery following rituximab may guide the management of steroid-refractory chronic GvHD.” Bone Marrow Transplant 51, no. 4 (April 2016): 607–9. https://doi.org/10.1038/bmt.2015.304.
       Full Text  Link to Item
    • Arai, Sally, Joseph Pidala, Iskra Pusic, Xiaoyu Chai, Samantha Jaglowski, Nandita Khera, Jeanne Palmer, et al. “A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.” Clin Cancer Res 22, no. 2 (January 15, 2016): 319–27. https://doi.org/10.1158/1078-0432.CCR-15-1443.
       Full Text  Open Access Copy  Link to Item
    • Shea, Thomas C., Christine Walko, Yunro Chung, Anastasia Ivanova, Julia Sheets, Kamakshi Rao, Don Gabriel, et al. “Phase I/II Trial of Dose-Escalated Busulfan Delivered by Prolonged Continuous Infusion in Allogeneic Transplant Patients.” Biol Blood Marrow Transplant 21, no. 12 (December 2015): 2129–35. https://doi.org/10.1016/j.bbmt.2015.07.016.
       Full Text  Link to Item
    • Flynn, Ryan, Jessica L. Allen, Leo Luznik, Kelli P. MacDonald, Katelyn Paz, Kylie A. Alexander, Ante Vulic, et al. “Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.” Blood 125, no. 26 (June 25, 2015): 4085–94. https://doi.org/10.1182/blood-2014-08-595470.
       Full Text  Link to Item
    • Baird, Kristin, Leora E. Comis, Galen O. Joe, Seth M. Steinberg, Fran T. Hakim, Jeremy J. Rose, Sandra A. Mitchell, et al. “Imatinib mesylate for the treatment of steroid-refractory sclerotic-type cutaneous chronic graft-versus-host disease.” Biol Blood Marrow Transplant 21, no. 6 (June 2015): 1083–90. https://doi.org/10.1016/j.bbmt.2015.03.006.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, and Jerome Ritz. “Aberrant B-cell homeostasis in chronic GVHD.” Blood 125, no. 11 (March 12, 2015): 1703–7. https://doi.org/10.1182/blood-2014-12-567834.
       Full Text  Link to Item
    • Hunsucker, Sally A., Colleen S. McGary, Benjamin G. Vincent, Atim A. Enyenihi, Jennifer P. Waugh, Karen P. McKinnon, Lisa M. Bixby, et al. “Peptide/MHC tetramer-based sorting of CD8⁺ T cells to a leukemia antigen yields clonotypes drawn nonspecifically from an underlying restricted repertoire.” Cancer Immunol Res 3, no. 3 (March 2015): 228–35. https://doi.org/10.1158/2326-6066.CIR-14-0001.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Bruce R. Blazar, Corey Cutler, and Jerome Ritz. “Reprint of: B cells in chronic graft-versus-host disease.” Biol Blood Marrow Transplant 21, no. 2 Suppl (February 2015): S11–18. https://doi.org/10.1016/j.bbmt.2014.12.033.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Bruce R. Blazar, Corey Cutler, and Jerome Ritz. “B cells in chronic graft-versus-host disease.” Biol Blood Marrow Transplant 21, no. 1 (January 2015): 16–23. https://doi.org/10.1016/j.bbmt.2014.10.029.
       Full Text  Link to Item
    • Flynn, Ryan, Jing Du, Rachelle G. Veenstra, Dawn K. Reichenbach, Angela Panoskaltsis-Mortari, Patricia A. Taylor, Gordon J. Freeman, et al. “Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans.” Blood 123, no. 25 (June 19, 2014): 3988–98. https://doi.org/10.1182/blood-2014-03-562231.
       Full Text  Link to Item
    • Jacobson, Caron A., Lixian Sun, Haesook T. Kim, Sean M. McDonough, Carol G. Reynolds, Michael Schowalter, John Koreth, et al. “Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease.” Biol Blood Marrow Transplant 20, no. 5 (May 2014): 668–75. https://doi.org/10.1016/j.bbmt.2014.01.021.
       Full Text  Link to Item
    • Allen, Jessica L., Prasanthi V. Tata, Matthew S. Fore, Jenna Wooten, Sharmistha Rudra, Allison M. Deal, Andrew Sharf, et al. “Increased BCR responsiveness in B cells from patients with chronic GVHD.” Blood 123, no. 13 (March 27, 2014): 2108–15. https://doi.org/10.1182/blood-2013-10-533562.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, and Maureen A. Su. “BAFF-ling autoantibodies.” J Clin Invest 123, no. 12 (December 2013): 5006–8. https://doi.org/10.1172/JCI73166.
       Full Text  Link to Item
    • Cutler, Corey, Haesook T. Kim, Bhavjot Bindra, Stefanie Sarantopoulos, Vincent T. Ho, Yi-Bin Chen, Jacalyn Rosenblatt, et al. “Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial.” Blood 122, no. 8 (August 22, 2013): 1510–17. https://doi.org/10.1182/blood-2013-04-495895.
       Full Text  Link to Item
    • Wood, W. A., J. Whitley, R. Goyal, P. M. Brown, A. Sharf, R. Irons, K. V. Rao, et al. “Effectiveness of etoposide chemomobilization in lymphoma patients undergoing auto-SCT.” Bone Marrow Transplant 48, no. 6 (June 2013): 771–76. https://doi.org/10.1038/bmt.2012.216.
       Full Text  Link to Item
    • Allen, Jessica L., Matthew S. Fore, Jenna Wooten, Philip A. Roehrs, Nazmim S. Bhuiya, Todd Hoffert, Andrew Sharf, et al. “B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways.” Blood 120, no. 12 (September 20, 2012): 2529–36. https://doi.org/10.1182/blood-2012-06-438911.
       Full Text  Link to Item
    • Fore, Matthew, Madan Jagasia, Stefanie Sarantopoulos, and Kristy L. Richards. “Further examination of BAFF SNPs in cGVHD.” Blood 120, no. 3 (July 19, 2012): 700–701. https://doi.org/10.1182/blood-2012-05-428409.
       Full Text  Link to Item
    • Fedoriw, Yuri, T Danielle Samulski, Allison M. Deal, Cherie H. Dunphy, Andrew Sharf, Thomas C. Shea, Jonathan S. Serody, and Stefanie Sarantopoulos. “Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development.” Biol Blood Marrow Transplant 18, no. 6 (June 2012): 968–73. https://doi.org/10.1016/j.bbmt.2012.03.005.
       Full Text  Link to Item
    • Levine, John E., Sophie Paczesny, and Stefanie Sarantopoulos. “Clinical applications for biomarkers of acute and chronic graft-versus-host disease.” Biol Blood Marrow Transplant 18, no. 1 Suppl (January 2012): S116–24. https://doi.org/10.1016/j.bbmt.2011.10.019.
       Full Text  Link to Item
    • Porcheray, Fabrice, David B. Miklos, Blair H. Floyd, Stefanie Sarantopoulos, Roberto Bellucci, Robert J. Soiffer, Joseph H. Antin, Edwin P. Alyea, Jerome Ritz, and Emmanuel Zorn. “Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation.” Transplantation 92, no. 3 (August 15, 2011): 359–65. https://doi.org/10.1097/TP.0b013e3182244cc3.
       Full Text  Link to Item
    • Coghill, James M., Stefanie Sarantopoulos, Timothy P. Moran, William J. Murphy, Bruce R. Blazar, and Jonathan S. Serody. “Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.” Blood 117, no. 12 (March 24, 2011): 3268–76. https://doi.org/10.1182/blood-2010-12-290403.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Kristen E. Stevenson, Haesook T. Kim, Whitney S. Washel, Nazmim S. Bhuiya, Corey S. Cutler, Edwin P. Alyea, et al. “Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease.” Blood 117, no. 7 (February 17, 2011): 2275–83. https://doi.org/10.1182/blood-2010-10-307819.
       Full Text  Link to Item
    • Armistead, Paul M., Shoudan Liang, Hua Li, Sijie Lu, Cornelis A. M. Van Bergen, Gheath Alatrash, Lisa St John, et al. “Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data.” Plos One 6, no. 8 (2011): e23217. https://doi.org/10.1371/journal.pone.0023217.
       Full Text  Link to Item
    • Ofran, Yishai, Haesook T. Kim, Vladimir Brusic, Loren Blake, Michael Mandrell, Catherine J. Wu, Stefanie Sarantopoulos, et al. “Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes.” Clin Cancer Res 16, no. 5 (March 1, 2010): 1642–51. https://doi.org/10.1158/1078-0432.CCR-09-2701.
       Full Text  Link to Item
    • Ho, Vincent T., Matthew Vanneman, Haesook Kim, Tetsuro Sasada, Yoon Joong Kang, Mildred Pasek, Corey Cutler, et al. “Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation.” Proceedings of the National Academy of Sciences of the United States of America 106, no. 37 (September 2009): 15825–30. https://doi.org/10.1073/pnas.0908358106.
       Full Text
    • Sarantopoulos, Stefanie, Kristen E. Stevenson, Haesook T. Kim, Corey S. Cutler, Nazmim S. Bhuiya, Michael Schowalter, Vincent T. Ho, et al. “Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease.” Blood 113, no. 16 (April 16, 2009): 3865–74. https://doi.org/10.1182/blood-2008-09-177840.
       Full Text  Link to Item
    • Sittler, Taylor, Jun Zhou, Joosang Park, Noah K. Yuen, Stefanie Sarantopoulos, Joseph Mollick, Ravi Salgia, Anita Giobbie-Hurder, Glenn Dranoff, and F Stephen Hodi. “Concerted potent humoral immune responses to autoantigens are associated with tumor destruction and favorable clinical outcomes without autoimmunity.” Clin Cancer Res 14, no. 12 (June 15, 2008): 3896–3905. https://doi.org/10.1158/1078-0432.CCR-07-4782.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Kristen E. Stevenson, Haesook T. Kim, Nazmim S. Bhuiya, Corey S. Cutler, Robert J. Soiffer, Joseph H. Antin, and Jerome Ritz. “High levels of B-cell activating factor in patients with active chronic graft-versus-host disease.” Clin Cancer Res 13, no. 20 (October 15, 2007): 6107–14. https://doi.org/10.1158/1078-0432.CCR-07-1290.
       Full Text  Link to Item
    • Sarantopoulos, Stefanie, Linrong Lu, and Harvey Cantor. “Qa-1 restriction of CD8+ suppressor T cells.” J Clin Invest 114, no. 9 (November 2004): 1218–21. https://doi.org/10.1172/JCI23152.
       Full Text  Link to Item
    • Lin, Nancy U., Stefanie Sarantopoulos, James R. Stone, Ilene Galinsky, Richard M. Stone, Daniel J. Deangelo, and Robert J. Soiffer. “Fatal hepatic necrosis following imatinib mesylate therapy.” Blood 102, no. 9 (November 1, 2003): 3455–56. https://doi.org/10.1182/blood-2003-07-2323.
       Full Text  Link to Item
    • Sharon, Jacqueline, Seshi R. Sompuram, Chiou-Ying Yang, Brent R. Williams, and Stefanie Sarantopoulos. “Construction of polyclonal antibody libraries using phage display.” Methods Mol Biol 178 (2002): 101–12. https://doi.org/10.1385/1-59259-240-6:101.
       Full Text  Link to Item
    • Sharon, J., S. Sarantopoulos, W. Den, C. Y. Kao, C. M. Baecher-Allan, K. E. Santora, S. R. Sompuram, S. Petersen-Mahrt, and B. R. Williams. “Recombinant polyclonal antibody libraries.” Comb Chem High Throughput Screen 3, no. 3 (June 2000): 185–96. https://doi.org/10.2174/1386207003331643.
       Full Text  Link to Item
    • Santora, K. E., S. Sarantopoulos, W. Den, S. Petersen-Mahrt, S. R. Sompuram, and J. Sharon. “Generation of a polyclonal fab phage display library to the human breast carcinoma cell line BT-20.” Comb Chem High Throughput Screen 3, no. 1 (February 2000): 51–57. https://doi.org/10.2174/1386207003327765.
       Full Text  Link to Item
    • Baecher-Allan, C. M., K. Santora, S. Sarantopoulos, W. Den, S. R. Sompuram, J. Sharon, A. M. Cevallos, N. Bhat, and H. Ward. “Generation of a polyclonal Fab phage display library to the protozoan parasite Cryptosporidium parvum.” Comb Chem High Throughput Screen 2, no. 6 (December 1999): 319–25.
       Link to Item
    • Den, W., S. R. Sompuram, S. Sarantopoulos, and J. Sharon. “A bidirectional phage display vector for the selection and mass transfer of polyclonal antibody libraries.” J Immunol Methods 222, no. 1–2 (January 1, 1999): 45–57. https://doi.org/10.1016/s0022-1759(98)00178-1.
       Full Text  Link to Item
    • Sarantopoulos, S., C. Y. Kao, W. Den, and J. Sharon. “A method for linking VL and VH region genes that allows bulk transfer between vectors for use in generating polyclonal IgG libraries.” J Immunol 152, no. 11 (June 1, 1994): 5344–51.
       Link to Item
    • Moyer, C. F., E. Huggins, S. Sarantopoulos, J. C. Lewis, D. Sajuthi, C. A. Biron, and C. L. Reinisch. “Cloned endothelium derived from autoimmune vascular disease retain structural and functional characteristics of normal endothelial cells.” Exp Cell Res 199, no. 1 (March 1992): 63–73. https://doi.org/10.1016/0014-4827(92)90462-h.
       Full Text  Link to Item

  • Conference Papers

    • Khera, Nandita, Betty K. Hamilton, Joseph A. Pidala, William A. Wood, Vicky Wu, Jenna Voutsinas, Lynn Onstad, et al. “Employment, Insurance, and Financial Experiences of Patients with Chronic Graft-versus-Host Disease in North America.” In Biol Blood Marrow Transplant, 25:599–605, 2019. https://doi.org/10.1016/j.bbmt.2018.09.040.
       Full Text  Link to Item
    • Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Gwynn D. Long, Richard Lopez, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Thiotepa, Total Body Irradiation, and Fludarabine Conditioning.” In Biol Blood Marrow Transplant, 23:1949–54, 2017. https://doi.org/10.1016/j.bbmt.2017.06.027.
       Full Text  Link to Item
    • Poe, J., J. diPaolo, W. Jia, J. Y. Kim, H. Su, N. Reyes, A. M. Marcondes, et al. “Oral Syk inhibitor, Entospletinib (GS-9973), controls disease and enhances survival in a mouse model of chronic graft-versus host disease (cGVHD).” In Bone Marrow Transplantation, 52:S46–S46. NATURE PUBLISHING GROUP, 2017.
       Link to Item
    • Anand, Sarah, Samantha Thomas, Kelly Corbet, Cristina Gasparetto, Richard Lopez, Gwynn D. Long, Ashley K. Morris, et al. “Adult Umbilical Cord Blood Transplantation Using Myeloablative Total Body Irradiation, Fludarabine, and Thiotepa Conditioning.” In Blood, 128:3395–3395. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.3395.3395.
       Full Text
    • Jia, Wei, Jonathan C. Poe, Hsuan Su, Glenn K. Matsushima, Jeffrey Rathmell, Kazuhiro Imai, Nancy J. Reyes, et al. “Recipient-Derived BAFF and Alloantigen Synergistically Activate B Cells in Murine Chronic Gvhd.” In Blood, 128:498–498. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.498.498.
       Full Text
    • Poe, Jonathan C., Wei Jia, Hsuan Su, Zhiguo Li, Frances T. Hakim, Steven Z. Pavletic, Jeremy J. Rose, et al. “All-Trans Retinoic Acid (ATRA) Targets IRF4 Deficient, NOTCH2-Activated B Cells from Chronic Gvhd Patients.” In Blood, 128:669–669. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.669.669.
       Full Text
    • Anand, S., S. Thomas, T. Hyslop, K. Corbet, C. Gasparetto, G. Long, A. Morris, et al. “Transplantation of Ex vivo Expanded Umbilical Cord Blood (Nicord) Results in Decreased Infection Burden and Hospital Length of Stay in the First 100 Days.” In Bone Marrow Transplantation, 51:S52–53. NATURE PUBLISHING GROUP, 2016.
       Link to Item
    • Friend, Reed, James Xenakis, Jonathan S. Serody, Terrance Comeau, Don A. Gabriel, Stefanie Sarantopoulos, James Coghill, et al. “Reduced Intensity Continuous Infusion Busulfan for Allogeneic Hematopoietic Cell Transplant Patients with Hematologic Disorders Who Are Ineligible or Inappropriate for Treatment with a More Intensive Therapeutic Regimen: LCCC 0306.” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.
       Link to Item
    • Poe, Jonathan C., Wei Jia, Zhiguo Li, Frances T. Hakim, Steven Z. Pavletic, Jeremy J. Rose, David A. Rizzieri, et al. “Targeting the Human Notch 2-BCR Axis: A Driver of B-Cell Hyper-Responsiveness in Active Chronic Graft-Versus Host Disease (cGVHD).” In Blood, Vol. 126. AMER SOC HEMATOLOGY, 2015.
       Link to Item
    • Fedoriw, Yuri, Lisa Cichon, Pouneh Dokouhaki, Stephanie Mathews, Andrew Sharf, and Stefanie Sarantopoulos. “Delayed Reconstitution of Bone Marrow B Cell Precursors After Allogeneic Stem Cell Transplantation Is Associated With Chronic Graft Versus Host Disease (cGVHD).” In Laboratory Investigation, 95:344A-344A. NATURE PUBLISHING GROUP, 2015.
       Link to Item
    • Fedoriw, Yuri, Lisa Cichon, Pouneh Dokouhaki, Stephanie Mathews, Andrew Sharf, and Stefanie Sarantopoulos. “Delayed Reconstitution of Bone Marrow B Cell Precursors After Allogeneic Stem Cell Transplantation Is Associated With Chronic Graft Versus Host Disease (cGVHD).” In Modern Pathology, 28:344A-344A. NATURE PUBLISHING GROUP, 2015.
       Link to Item
    • Green, Michael M. B., Mitchell E. Horwitz, Yubin Kang, Nelson J. Chao, Gwynn D. Long, David Rizzieri, Cristina Gasparetto, et al. “Administration of Plerixafor (a CXCR4 antagonist) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Enhances Platelet Recovery in a Phase I/II Trial.” In Biology of Blood and Marrow Transplantation, 21:S31–32. Elsevier BV, 2015. https://doi.org/10.1016/j.bbmt.2014.11.024.
       Full Text
    • Shea, Thomas C., Christine M. Walko, Yunro Chung, Anastasia Ivanova, Kamakshi V. Rao, James Coghill, Stefanie Sarantopoulos, et al. “Differential Impact of Dose Escalated Busulfan on Allogeneic Transplant for High, Intermediate and Low Risk Disease.” In Biology of Blood and Marrow Transplantation, 21:S310–S310. Elsevier BV, 2015. https://doi.org/10.1016/j.bbmt.2014.11.494.
       Full Text
    • Allen, Jessica L., George Fedoriw, Jenna Wooten, Matthew Fore, Philip A. Roehrs, Paul Armistead, James Coghill, et al. “Increased BLNK and Syk in B Cells From Chronic Graft-Versus-Host Disease Patients: Identification of Novel Therapeutic Targets.” In Biology of Blood and Marrow Transplantation, 19:S136–37. Elsevier BV, 2013. https://doi.org/10.1016/j.bbmt.2012.11.075.
       Full Text
    • Wood, William A., Allison M. Deal, Bryce B. Reeve, Amy P. Abernethy, Claudio L. Battaglini, Yoon Hie Kim, Julia S. Whitley, et al. “Feasibility of Daily and Weekly Symptom and Health-Related Quality of Life (HRQOL) Surveillance in Patients Receiving Hematopoietic Cell Transplantation (HCT).” In Blood, 120:4471–4471. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.4471.4471.
       Full Text
    • Wood, William A., Allison M. Deal, Claudio L. Battaglini, Bryce B. Reeve, Amy P. Abernethy, Yoon Hie Kim, Julia S. Whitley, et al. “Feasibility and Prognostic Value of VO2peak in Patients Undergoing Hematopoietic Cell Transplantation (HCT).” In Blood, 120:4152–4152. American Society of Hematology, 2012. https://doi.org/10.1182/blood.v120.21.4152.4152.
       Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.