Skip to main content

Stefanie Sarantopoulos

Chief of Hematologic Malignancies and Cellular Therapy
Medicine, Hematologic Malignancies and Cellular Therapy
Duke Blood Cancer Center 2400 Pratt St., Suite 5000, Box 3961, Durham, NC 27705
2400 Pratt Street Floor 5, Box 3961, Durham, NC 27710

Selected Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of Allergy and Infectious Diseases · 2018 - 2029

The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028

Harnessing B Cells after Stem Cell Transplant to Produce Novel CAR-Ts

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2027

Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026

The Role of the DNA Sensor AIM2 in B Cell Fate and Function After HCT

ResearchPrincipal Investigator · Awarded by Leukemia & Lymphoma Society · 2024 - 2026

B Cell-Fibroblast Crosstalk Promotes Chronic GVHD of the Lung

ResearchMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2026

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 1975 - 2026

Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2026

Basic Immunology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025

DABAT - DNA-sensing by AIM2 in activated B cells: novel targets to improve Allogeneic haematopoietic stem cell Transplantation

FellowshipPrincipal Investigator · Awarded by Universite de Bordeaux · 2020 - 2023

T32 UNC - Duke Immunotherapy Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by University of North Carolina - Chapel Hill · 2021 - 2022

Medical Scientist Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1997 - 2022

Breaking B-Cell Tolerance to Produce Antibodies that Eradicate Leukemias and Lymphomas

ResearchPrincipal Investigator · Awarded by Department of Defense · 2018 - 2021

The Notch2-BCR Axis: Targeting Drivers of B cell Fate in Chronic GVHD

ResearchPrincipal Investigator · Awarded by Leukemia & Lymphoma Society · 2015 - 2019

Understanding Aberrant TLR7 Signaling in B Cells from Patients with Chronic GVHD

FellowshipPrincipal Investigator · Awarded by American Society for Blood and Marrow Transplantation · 2018 - 2019

A Phase II of Entospletinib, a SYK Inhibitor, First line cGVHD patients

Clinical TrialPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2016 - 2019

The Effects of Syk Blockade with GS-9973 on Immunity in a Murine Model of GVHD

ResearchPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2016 - 2018

Improving Outcomes Assessment in cGVHD

ResearchPrincipal Investigator · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2018

BAFF-Driven Targeted Immunotherapy for Patients with Leukemia

ResearchPrincipal Investigator · Awarded by Department of Defense · 2011 - 2015

BAFF Pathology: Novel Therapeutic Targets in Chronic Graft versus Host Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2011 - 2015

Fellowships, Gifts, and Supported Research


T32 Immunotherapy Duke-UNC · 2018 Awarded by: NIH Awarded to William McManigle MD in my lab
ASBMT Young Investigator Award · 2018 Awarded by: American Society of Bone Marrow Transplantation Awarded to Amy Suthers, PhD in my lab
Duke Scholar Award · 2017 Awarded by: Duke University

External Relationships


  • ASTCT (American Society of Transplantation and Cellular Therapy)
  • Incyte Corporation
  • Rigel Pharmaceuticals Inc advisory board once Jan 2020--COMPLETED; Rigel provides fostamatinib for our NIH-funded Duke clinical trial (I hold IND)
  • Rigel Pharmaceuticals, Inc
  • Sanofi
  • nference

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.