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Stefanie Sarantopoulos

Chief of Hematologic Malignancies and Cellular Therapy
Medicine, Hematologic Malignancies and Cellular Therapy
Duke Blood Cancer Center 2400 Pratt St., Suite 5000, Box 3961, Durham, NC 27705
2400 Pratt Street Floor 5, Box 3961, Durham, NC 27710

Selected Grants


Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028

The Role of the DNA Sensor AIM2 in B Cell Fate and Function After HCT

ResearchPrincipal Investigator · Awarded by Leukemia & Lymphoma Society · 2024 - 2027

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026

B Cell-Fibroblast Crosstalk Promotes Chronic GVHD of the Lung

ResearchMentor · Awarded by National Institutes of Health · 2024 - 2026

Hematology & Transfusion Medicine (T32)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1975 - 2026

Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2026

Basic Immunology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025

DABAT - DNA-sensing by AIM2 in activated B cells: novel targets to improve Allogeneic haematopoietic stem cell Transplantation

FellowshipPrincipal Investigator · Awarded by Universite de Bordeaux · 2020 - 2023

T32 UNC - Duke Immunotherapy Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by University of North Carolina - Chapel Hill · 2021 - 2022

Medical Scientist Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1997 - 2022

Breaking B-Cell Tolerance to Produce Antibodies that Eradicate Leukemias and Lymphomas

ResearchPrincipal Investigator · Awarded by Department of Defense · 2018 - 2021

The Notch2-BCR Axis: Targeting Drivers of B cell Fate in Chronic GVHD

ResearchPrincipal Investigator · Awarded by Leukemia & Lymphoma Society · 2015 - 2019

Understanding Aberrant TLR7 Signaling in B Cells from Patients with Chronic GVHD

FellowshipPrincipal Investigator · Awarded by American Society for Blood and Marrow Transplantation · 2018 - 2019

A Phase II of Entospletinib, a SYK Inhibitor, First line cGVHD patients

Clinical TrialPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2016 - 2019

The Effects of Syk Blockade with GS-9973 on Immunity in a Murine Model of GVHD

ResearchPrincipal Investigator · Awarded by Gilead Sciences, Inc. · 2016 - 2018

Improving Outcomes Assessment in cGVHD

ResearchPrincipal Investigator · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2018

BAFF-Driven Targeted Immunotherapy for Patients with Leukemia

ResearchPrincipal Investigator · Awarded by Department of Defense · 2011 - 2015

BAFF Pathology: Novel Therapeutic Targets in Chronic Graft versus Host Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2011 - 2015

Fellowships, Gifts, and Supported Research


T32 Immunotherapy Duke-UNC · 2018 Awarded by: NIH Awarded to William McManigle MD in my lab
ASBMT Young Investigator Award · 2018 Awarded by: American Society of Bone Marrow Transplantation Awarded to Amy Suthers, PhD in my lab
Duke Scholar Award · 2017 Awarded by: Duke University

External Relationships


  • 11th Annual Guangzhou International Forum supported by the Guangdong Province Anti-Cancer Association --over zoom, no travel involved
  • ASTCT (American Society of Transplantation and Cellular Therapy)
  • European Bone Marrow Transplant (EBMT) meeting--gave a talke Saturday March 19,2022 - on zoom
  • Grant from the European Commission in collaobation with INserm/Bordeaux Univ in France, Dr. Jonathan Visentin, has been awarded and is pending;
  • Incyte
  • Incyte Corporation
  • NIH/NCI, working on consensus criteria for chronic GVHD (Steve Pavletic lead at NCI)
  • Rigel Pharmaceuticals Inc advisory board Jan 2020 and now signed consulting contract; Rigel also supplies the drug, fostamatinib (also called TAvalese) for our NIH-funded Duke clinical trial
  • Rigel Pharmaceuticals, Inc
  • The American Society of Hematology (ASH)

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.