Uninvolved skin from psoriatic patients develops signs of involved psoriatic skin after being grafted onto nude mice.


Journal Article

Clinically involved psoriatic epidermis maintains its histological appearance, increased labeling index, and increased level of plasminogen activator after being grafted onto athymic nude mice. Uninvolved psoriatic epidermis develops increases in plasminogen activator activity after being grafted onto athymic nude mice; this is accompanied by an increased labeling index. Thus, psoriatic skin can develop markers of psoriasis independent of the host.

Full Text

Duke Authors

Cited Authors

  • Fraki, JE; Briggaman, RA; Lazarus, GS

Published Date

  • February 5, 1982

Published In

Volume / Issue

  • 215 / 4533

Start / End Page

  • 685 - 687

PubMed ID

  • 7036342

Pubmed Central ID

  • 7036342

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.7036342


  • eng

Conference Location

  • United States