Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.


Journal Article

Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for STS provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumors, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines discusses general principles for the diagnosis, staging, and treatment of STS of the extremities, superficial trunk, or head and neck; outlines treatment recommendations by disease stage; and reviews the evidence to support the guidelines recommendations.

Full Text

Duke Authors

Cited Authors

  • von Mehren, M; Randall, RL; Benjamin, RS; Boles, S; Bui, MM; Ganjoo, KN; George, S; Gonzalez, RJ; Heslin, MJ; Kane, JM; Keedy, V; Kim, E; Koon, H; Mayerson, J; McCarter, M; McGarry, SV; Meyer, C; Morris, ZS; O'Donnell, RJ; Pappo, AS; Paz, IB; Petersen, IA; Pfeifer, JD; Riedel, RF; Ruo, B; Schuetze, S; Tap, WD; Wayne, JD; Bergman, MA; Scavone, JL

Published Date

  • May 2018

Published In

Volume / Issue

  • 16 / 5

Start / End Page

  • 536 - 563

PubMed ID

  • 29752328

Pubmed Central ID

  • 29752328

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2018.0025


  • eng

Conference Location

  • United States