Muscle Oxygen Dynamics During Cycling Exercise in Angina Pectoris Patients.

Conference Paper

Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and ∆deoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ∆SmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = -0.52, p < 0.05), and ∆deoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.

Full Text

Duke Authors

Cited Authors

  • Takagi, S; Murase, N; Kime, R; Niwayama, M; Osada, T; Katsumura, T

Published Date

  • 2016

Published In

Volume / Issue

  • 923 /

Start / End Page

  • 291 - 297

PubMed ID

  • 27526156

International Standard Serial Number (ISSN)

  • 0065-2598

Digital Object Identifier (DOI)

  • 10.1007/978-3-319-38810-6_39

Conference Location

  • United States