Scholars@Duke
Journal cover image

Magnesium deficiency prolongs myocardial stunning in an open-chest swine model.

Publication ,  Journal Article
Herzog, WR; Atar, D; Mak, IT; Alyono, D; MacCord, C; Weglicki, WB
Published in: Int J Cardiol
December 1994
Published version (DOI) Link to item

The effect of magnesium deficiency on postischemic myocardial dysfunction (myocardial stunning) in an open-chest swine model was studied. Twelve swine were assigned either to low magnesium diet or control diet. Myocardial stunning was assessed by measuring regional wall thickening by epicardial Doppler before and after brief occlusion (8 min) of the left anterior descending coronary artery. Serum magnesium levels decreased significantly in the experimental group only. Glutathione levels were 42.6% lower in the magnesium deficient swine than in controls. Stunning time was significantly prolonged from 32.8 +/- 3.1 min in the control group to 43.8 +/- 4.6 min in the hypomagnesemic swine. In conclusion, magnesium deficiency is associated with prolonged recovery from myocardial stunning.

Duke Scholars

William Raymond Herzog
Author William Raymond Herzog Medicine, Cardiology

Published In

Int J Cardiol

DOI

10.1016/0167-5273(94)90176-7

ISSN

0167-5273

Publication Date

December 1994

Volume

47

Issue

2

Start / End Page

105 / 115

Location

Netherlands

Related Subject Headings

  • Time Factors
  • Myocardial Stunning
  • Myocardial Reperfusion
  • Myocardial Contraction
  • Models, Cardiovascular
  • Magnesium Deficiency
  • Magnesium
  • Hemodynamics
  • Heart Function Tests
  • Glutathione
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Herzog, W. R., Atar, D., Mak, I. T., Alyono, D., MacCord, C., & Weglicki, W. B. (1994). Magnesium deficiency prolongs myocardial stunning in an open-chest swine model. Int J Cardiol, 47(2), 105–115. https://doi.org/10.1016/0167-5273(94)90176-7
Herzog, W. R., D. Atar, I. T. Mak, D. Alyono, C. MacCord, and W. B. Weglicki. “Magnesium deficiency prolongs myocardial stunning in an open-chest swine model.” Int J Cardiol 47, no. 2 (December 1994): 105–15. https://doi.org/10.1016/0167-5273(94)90176-7.
Herzog WR, Atar D, Mak IT, Alyono D, MacCord C, Weglicki WB. Magnesium deficiency prolongs myocardial stunning in an open-chest swine model. Int J Cardiol. 1994 Dec;47(2):105–15.
Herzog, W. R., et al. “Magnesium deficiency prolongs myocardial stunning in an open-chest swine model.” Int J Cardiol, vol. 47, no. 2, Dec. 1994, pp. 105–15. Pubmed, doi:10.1016/0167-5273(94)90176-7.
Herzog WR, Atar D, Mak IT, Alyono D, MacCord C, Weglicki WB. Magnesium deficiency prolongs myocardial stunning in an open-chest swine model. Int J Cardiol. 1994 Dec;47(2):105–115.
Journal cover image

Published In

Int J Cardiol

DOI

10.1016/0167-5273(94)90176-7

ISSN

0167-5273

Publication Date

December 1994

Volume

47

Issue

2

Start / End Page

105 / 115

Location

Netherlands

Related Subject Headings

  • Time Factors
  • Myocardial Stunning
  • Myocardial Reperfusion
  • Myocardial Contraction
  • Models, Cardiovascular
  • Magnesium Deficiency
  • Magnesium
  • Hemodynamics
  • Heart Function Tests
  • Glutathione