Energy Constraint as a Novel Mechanism Linking Exercise and Health.

Journal Article (Review;Journal Article)

Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This exercise-induced downregulation improves health at moderate levels of physical activity but can be detrimental at extreme workloads.

Full Text

Duke Authors

Cited Authors

  • Pontzer, H

Published Date

  • November 2018

Published In

Volume / Issue

  • 33 / 6

Start / End Page

  • 384 - 393

PubMed ID

  • 30303776

Pubmed Central ID

  • 30303776

Electronic International Standard Serial Number (EISSN)

  • 1548-9221

International Standard Serial Number (ISSN)

  • 1548-9213

Digital Object Identifier (DOI)

  • 10.1152/physiol.00027.2018


  • eng