Are low-carbohydrate diets safe in diabetic and nondiabetic chronic kidney disease?

Journal Article (Journal Article;Review)

Diabetes mellitus and obesity both contribute to chronic kidney disease (CKD) and diabetic kidney disease (DKD), and they can accelerate the loss of kidney function. Dietary intake can potentially have wide-reaching effects on the risk of CKD/DKD and their progression by reducing weight and blood pressure, improving glycemic control, reducing hyperfiltration, and modulating inflammation. Low-carbohydrate (LC) diets can reduce weight and improve glycemic control, but the relatively higher protein content also raises concern in CKD/DKD. Empiric evidence supporting the kidney-related benefits or risks of LC diets is needed to understand the balance of these potential harms and benefits for patients with DKD and is the subject of our review.

Full Text

Duke Authors

Cited Authors

  • Mitchell, NS; Scialla, JJ; Yancy, WS

Published Date

  • February 2020

Published In

Volume / Issue

  • 1461 / 1

Start / End Page

  • 25 - 36

PubMed ID

  • 30644556

Pubmed Central ID

  • PMC6629514

Electronic International Standard Serial Number (EISSN)

  • 1749-6632

Digital Object Identifier (DOI)

  • 10.1111/nyas.13997


  • eng

Conference Location

  • United States