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William Samuel Yancy Jr.

Professor of Medicine
Medicine, General Internal Medicine
501 Douglas Street, Duke Diet & Fitness Center, Durham, NC 27705

Overview


Impact of obesity on health, health care delivery, quality of life.
Diet and other weight loss interventions
Preventive medicine

Current Duke Appointments & Affiliations


Professor of Medicine · 2021 - Present Medicine, General Internal Medicine, Medicine

Recent News Items


Published February 9, 2024
Does Weight Loss Help Before Knee Surgery? Duke Experts Explain.
Published November 5, 2019
To Improve Diabetes Outcomes, Add Weight Loss Counseling to Treatment
Published April 28, 2016
Visiting to lose weight, then calling it home

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Recent Scholarly Works


Partner Weight Loss and Diet Outcomes at 24 Months in a Randomized Controlled Trial of a Dyadic Versus Individual Weight Management Intervention.

Journal article Obes Sci Pract · August 2026 BACKGROUND: Including romantic partners as supports in behavioral weight management programs targeting index participants could yield spillover effects, but few studies have explored the effects on partners. METHODS: Dyads included an index participant wit ... Full text Link to item Cite

Study protocol for Log2Lose: A randomized controlled trial to evaluate financial incentives for dietary self-monitoring and interim weight loss in adults with obesity.

Journal article Contemp Clin Trials · September 2025 Although behavioral weight-loss programs are efficacious for achieving clinically significant weight loss, adherence to such programs is variable. Positive reinforcement through small financial incentives has shown promise for increasing adherence to behav ... Full text Link to item Cite

Opportunities for General Internal Medicine to Promote Equity in Obesity Care.

Journal article J Gen Intern Med · July 2025 The number and complexity of obesity treatments has increased rapidly in recent years. This is driven by the approval of new anti-obesity medications (AOMs) that produce larger degrees of weight loss than previously approved AOMs. Unfortunately, access to ... Full text Link to item Cite
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Recent Grants


2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Center for Advancing Translational Sciences · 2025 - 2030

TRANSFORM

Clinical TrialPrincipal Investigator · Awarded by Cleerly, Inc · 2025 - 2030

A gut sense for dietary lysine

ResearchCollaborator · Awarded by National Institutes of Health · 2026 - 2030

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Education


East Carolina University · 1995 M.D.