Probing Computation in the Primate Visual System at Single-Cone Resolution.

Journal Article (Journal Article;Review)

Daylight vision begins when light activates cone photoreceptors in the retina, creating spatial patterns of neural activity. These cone signals are then combined and processed in downstream neural circuits, ultimately producing visual perception. Recent technical advances have made it possible to deliver visual stimuli to the retina that probe this processing by the visual system at its elementary resolution of individual cones. Physiological recordings from nonhuman primate retinas reveal the spatial organization of cone signals in retinal ganglion cells, including how signals from cones of different types are combined to support both spatial and color vision. Psychophysical experiments with human subjects characterize the visual sensations evoked by stimulating a single cone, including the perception of color. Future combined physiological and psychophysical experiments focusing on probing the elementary visual inputs are likely to clarify how neural processing generates our perception of the visual world.

Full Text

Duke Authors

Cited Authors

  • Kling, A; Field, GD; Brainard, DH; Chichilnisky, EJ

Published Date

  • July 8, 2019

Published In

Volume / Issue

  • 42 /

Start / End Page

  • 169 - 186

PubMed ID

  • 30857477

Pubmed Central ID

  • PMC6996509

Electronic International Standard Serial Number (EISSN)

  • 1545-4126

Digital Object Identifier (DOI)

  • 10.1146/annurev-neuro-070918-050233


  • eng

Conference Location

  • United States