Overview
My laboratory studies how the retina processes visual scenes and transmits this information to the brain. We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.
Current Appointments & Affiliations
Adjunct Associate Professor of Neurobiology
·
2023 - Present
Neurobiology,
Basic Science Departments
Faculty Network Member of the Duke Institute for Brain Sciences
·
2015 - Present
Duke Institute for Brain Sciences,
University Institutes and Centers
Recent Publications
Author Correction: Biophysical neural adaptation mechanisms enable artificial neural networks to capture dynamic retinal computation.
Journal Article Nat Commun · March 14, 2025 Full text Link to item CiteFunctional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds.
Preprint · December 20, 2024 Full text Link to item CiteFunctional diversity in the output of the primate retina.
Preprint · November 1, 2024 Full text Link to item CiteRecent Grants
Real-time mapping and adaptive testing for neural population hypotheses
ResearchAdvisor · Awarded by National Institutes of Health · 2022 - 2025Bridging gap in comparative biology using the tree shrew visual system
ResearchMentor · Awarded by National Institutes of Health · 2021 - 2023In Vivo Modeling of Mitochondrial Complex I Deficiency in Retinal Ganglion Cells
ResearchAdvisor · Awarded by National Institutes of Health · 2018 - 2023View All Grants
Education, Training & Certifications
University of Washington ·
2004
Ph.D.